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单词 Primary ciliary dyskinesia
释义

Primary ciliary dyskinesia

英语百科

Primary ciliary dyskinesia

Axial CT image showing situs inversus. The liver is normally on the right side of the body and the spleen on the left, they are switched in this patient with situs inversus.
Axial CT image showing dextrocardia with the IVC and morphologic right ventricle on the left and the left ventricle on the right.
Axial CT image showing chronic sinusitis in an individual with Kartagener syndrome.

Primary ciliary dyskinesia (PCD), also immotile ciliary syndrome or Kartagener syndrome, is a rare, ciliopathic, autosomal recessive genetic disorder that causes defects in the action of cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube, as well as in the flagella of sperm cells. The phrase "immotile ciliary syndrome" is no longer favored as the cilia do have movement, but may be inefficient or unsychronized.

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