Bill say he wants to be in at the kill, because he is Frank's friend.

At the end of the second season, the last bullet is used to kill Azazel, and the gun is thought to be useless. However, Ruby later assists Bobby in repairing the gun so that it can use more bullets.

Wu hopes one day to be able to find tiny prostate cancer metastases in patients and kill them at the same time, watching it all on a PET scanner.