It is suggested to increase arsenicsalt test items in the quality standards of trichosanthin.
建议天花粉的质量标准中增加砷盐检测项。
2
Method: according to "Chinese Pharmacopoeia" (ChP) (2010) part I, we exam impurity of heavy metal and arsenicsalt.
方法:参考《中国药典》(2010)i部方法对重金属、砷盐进行杂质限量检查。
3
CONCLUSION: Crude realgar could induce significant liver oxidative injury, which could be reduced by purified realgar. Soluble arsenicsalt may be major toxic ingredient.