Purpose and methods: Single cell gel electrophoresis (SCGE), sisterchromatidexchanges (SCE), chromosome aberrations are three methods to determine DNA damage and repair.
Several studies have shown that SO2 and its derivatives could induce chromosomal aberrations, sisterchromatidexchanges and micronuclei in human blood lymphocyte, bone marrow cell in mice and CHL.
The paper makes an observation and statistical study of 28 cases in drinking group and 22 cases in control group with peripheric blood of lymphatic sisterchromatidexchanges (SCE).