The optimal co-ordination mode for the hydration of complementary bases G-C, A-T in B-DNA molecule has been derived by using quantum chemical calculations and empirical potential energy functions.

Those are also symptoms of a deficiency of B-12, a key nutrient needed to make red blood cells and DNA and keep the nervous system working right.

Franklin's achievement was to discover that previous X-ray photos of DNA were hard to interpret because DNA crystallizes in two forms, known as a and b, depending on their water content.