This identified an unexpectedly high frequency of mutations involving genes that function as master regulators of normal B-cell development and differentiation.
他们确定了一个基因的意外高频突变，此基因是正常B细胞发生和分化的主要调节基因。
2
The abnormal differentiation of T-cell subsets in chronic hepatic B, lowering of CD4, and rise of CD8, can serve as an index for observing the disease state.
慢性乙型肝炎T-淋巴细胞亚群分化异常，CD4下降，CD8升高可作为病情观察的指标。
3
This result confirmed that CD43 is a surface marker of Bcell expressed increasely after the activation and differentiation of Bcell.