Calcium is stored in the endoplasmic reticulum (er), where it is buffered by calcium binding chaperones such as calnexin and calreticulin, and is released via the IP3 Receptor channel (1).
Through the signal pathway of L-type calcium channel on the cytomembrane, NPY-Y1 receptor could increase the proliferation of SMCs.
结论通过细胞膜上L型钙离子通道进行跨膜信号传递，NPY-Y1受体介导促血管平滑肌细胞增殖作用。
3
CONCLUSION Rhubarb has exciting actions on isolated antral circular strips of guinea pig, which is partly mediated via cholinergic M receptor, cholinergic N receptor and L-type calcium channel.