| 释义 |
mammalian target of rapamycin - 雷帕霉素哺乳动物靶蛋白：mTOR（雷帕霉素哺乳动物靶蛋白），也称为机械靶蛋白酶，有时被称为FK506结合蛋白12-雷帕霉素相关蛋白1（FRAP1），是一种激酶，在人体中由MTOR基因编码。mTOR是磷脂酰肌醇3激酶相关激酶家族的成员。
1 ?雷帕霉素靶蛋白 但究竟是形成LAP还是形成LIP，这又取诀于一个分子信号发生器mTOR的活性，是mammalian Target of Rapamycin（雷帕霉素靶蛋白）的缩写。雷帕霉素（Rapamycin）是一种可抑制mTOR的药物，但对于免疫系统有非常强的反作用。 2 ?哺乳动物雷帕霉素靶点 哺乳动物雷帕霉素靶点(Mammalian target of rapamycin, mTOR)是自噬的一个主调控器。有研究表明,在哺乳动物细胞中,mTORCl激酶可能通过调节ULK1复合物的活性来抑制自噬的发生。 3 ?哺乳动物类雷帕霉素靶蛋白 -? 哺乳动物类雷帕霉素靶蛋白(mammalian target of rapamycin, mTOR)是经过临床验证的肿瘤靶标,但PI3K-AKT-mTOR通路抑制剂是否可用于治疗mTOR基因突变的黑色素瘤患者,目.. 4 ?靶蛋白 哺乳类动物雷帕霉素靶蛋白（mammalian target of rapamycin,mTOR）作为一种重要的信号传导分子，参与细胞的多种生理和病理过程，在细胞的生存、生长及增殖过程中起中心调控作...
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The Novartis drug suppresses a protein called MTOR (mammalian target of rapamycin), which receives incoming growth signals from the surface of the cell and directs them to grow fatter, a necessary step before cell division. FORBES: Magazine Article - 2.
The active ingredient in Rapamune, rapamycin, was discovered decades ago but scientists didn't understand how the drug worked until a graduate student named David Sabatini discovered the mammalian target of rapamycin (mTOR), a protein that acts as part of a complicated set of chemical signals that causes cells to divide. FORBES: Magazine Article
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