The chemical modification of sugar moiety in nucleoside or nucleotide is always an important way to discover new lead compounds with anti-viral, anti-tumor and other biological activities.

Conclusion Positive control of blood sugar is the key to cure malignant tumor with diabetes clinically.

The results showed that there were bigger genetic coefficients of variation and higher heritability for vitamin C, reducing sugar, organic acid, fruit tumor, fruit color, fruit thorn and bitterness;