The standard assay for newborn CMV screening is rapid culture performed on saliva specimens obtained at birth, but this assay cannot be automated.

For example, the mouse assay that is still the gold standard for botulinum neurotoxin detection (3) is both costly and difficult to deploy.

AIM: to make trial preparation of paracetamol nose drops and define its quality standard, assay method of content, storage requirement, period of validity, safety and effectiveness.