Conclusion Wrinkle formation in photoaging skin after PUVAtherapy is correlated with the imbalance of expression of matrix metalloproteinases and their inhibitors of dermal fibroblasts.
Objective: To assess the efficacy and safety of modified PUVAtherapy in the treatment of chronic plaque-type psoriasis.
目的:探索用改良PUVA疗法治疗慢性斑块性银屑病的疗效和安全性。
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CONCLUSION Psoralen loaded PLGA nanospartilcles might be a promising transdermal delivery system in order to improve the efficacy and reduce the side effects in the PUVAtherapy.