BACKGROUND: chronic pain conditions may result from peripheral nerve injury, chronic peripheral inflammation, or sensoryganglia inflammation.
研究背景：外周神经损伤及慢性炎症或感觉神经节炎症可导致慢性疼痛状态。
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Substance P-containing neurons and somatostatin-containing neurons in the somatic sensoryganglia might play certain role in the transmission and integration of somatic sensory information.
躯体感觉神经节内的P物质和生长抑素神经元，在躯体感觉信息的传导和整合中，可能发挥一定的作用。
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OBJECTIVE: To observe the protective effect of Schwann cell-derived neurotrophic factor on the high injury of peripheral nerve-induced apoptosis of sensory neurons in spinal dorsal root ganglia.