In the brains of the treated mice, the researchers found changes in the activity of genes that encode portions of the receptor for the neurotransmiter GABA.
The molecule blocked a gene that codes for a receptor for GABA, a brain signaling molecule.
该分子抑制了产生氨基丁酸受体这种大脑内信号分子的基因片段。
3
This finding suggests ways to improve anxiolytics and to develop drugs for other neurological disorders based on their specificity for GABA(A) receptor subtypes in distinct neuronal circuits.