Endothelin receptor antagonists are known to have health benefit but precisely why was an unknown, said Pollock, corresponding author on the study.

The author also discussed the methods of the animal model of the subarachnoid hemorrhage and the effect of endothelin receptor on the cerebral vasospasm caused by subarachnoid hemorrhage.

Conclusion the endothelin receptor antagonist BQ 123 does provide a certain degree of protection for kidneys from the early stage of IARF.