PTTG mRNA in the pituitary glands was regulated by estradiol, with possible involvement in estradiol induced tumorigenesis in rats.
垂体瘤转化基因参与调节雌激素诱导的大鼠垂体腺瘤发生。
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Methods: Transfect plasmid which carries PTTG gene use liposome, constructs the pituitary cell line which high express PTTG gene, observe the cell form.
方法：用脂质体转染携带PTTG基因的表达质粒，构建过表达PTTG基因的垂体细胞株，观察细胞形态。
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Conclusion: (1) High expressed the PTTG gene in the normal pituitary gland cell also to be possible to cause the cell cancer, enhancement attack ability.