AIM: To establish the experimental acute pulmonary embolism (APE) model and observe the left and right ventricular pressure-volume relationship in different overload situations.

Pressure volume(P V) relationship of rabbits femoral veins was measured and the microstructure of the veins was observed.

And it was supposed that the influence of the pressure on the system is only effect upon the exess molar volume of the system rely on the relationship of Gibbs free enthalpy with the pressure.