The invention discloses a recombinant vector co-expressed by medicament metabolizing enzyme P450 2e1 of cynomolgus monkey and REDOXenzyme P450 of cynomolgus monkey.
The review describes the challenges of constructing and applying REDOXenzyme devices, including the poor electrical contact between electrodes and enzymes and low lifetime and scalability of devices.
Such methods can be used in particular to monitor non-redoxenzyme reactions, such as kinase, phosphatase, or protease reactions, although REDOXenzyme reactions can also be monitored by such methods.