Conclusions: The ambroxol HCl osmotic pump controlled release tablets have a stable releasecurve and conform to zero release order.
结论：盐酸氨溴索渗透泵控释片释药稳定，零级释药明显，具备优良控释制剂的特征。
2
The mechanism of release results from the matrix rode and drug diffusion of matrix by describing the drug releasecurve using Ringer-Peppas model.
释药机制探讨表明：经膜控和骨架杂化控制释药的模型用一级动力学方程解释较好。
3
The drug loading, entrapment efficiency, diameter of nanoparticles and particle diameter distribution, shape and releasecurve of nanoparticles were investigated in vitro.