Patients who suffer from allergy to shellfish may be allergic to iodine, and should consult their physician regarding pre-medication to lessen risk of allergic reaction.

While we have not seen dose-limiting toxicity at this level with the slower infusion (without pre-medication), we have seen headache in two patients, which is a moderate adverse effect.

The investigators used the Diabetes Medication Satisfaction questionnaire (DiabMedSat), to compare quality of life pre - and post-treatment.