Objective To study the effect of FK506 on renalhypertrophy and its mechanism in early diabetic rats.
目的探讨FK506对糖尿病大鼠早期肾脏肥大的抑制作用及机制。
2
Objective to investigate the expression of connective tissue growth factor (CTGF) in the kidney of STZ induced diabetic rats and its relationship with the early renalhypertrophy.
Conclusion the protective effect of valsartan on diabetic kidney may be partly through inhibiting renalhypertrophy by regulating the expression of cell cycle related protein P27.