OBJECTIVE To study the formulation, preparation and dissolution of amoxicillin and clavulanatepotassium tablets.
目的：研究阿莫西林克拉维酸钾片处方及工艺，并考察其溶出度。
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Objective: to establish a high performance liquid chromatography method for simultaneous determination of amoxicillin and clavulanatepotassium in amoxicillin and clavulanatepotassium granules.
目的：建立高效液相色谱法同时测定阿莫西林克拉维酸钾颗粒中阿莫西林和克拉维酸钾的含量。
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METHODS The impurity profiling changes of amoxicillin plus potassiumclavulanate were compared with both amoxicillin and potassiumclavulanate alone by HPLC.