However, the recent report of GNAS mutations being detected in a significant proportion of parosteal osteosarcoma challenges the specificity of this mutation.
然而,最新的检测报道发现在很大一部分骨旁骨肉瘤中有GNAS突变,对该基因突变的特异性提出了质疑。
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Our findings therefore support prior observations that GNAS mutations are highly specific for fibrous dysplasia and occur rarely, if ever, in parosteal and other low-grade osteosarcomas.