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1 ?米卡芬净 ...用药,但因其安全性和耐受性不佳,传统剂型和脂质体剂型均可导致肾毒性和急性输注相关的毒性。因此,研制和开发新型抗真菌药成为当务之急,米卡芬净(micafungin)是2001年由美国默克公司研究开发的半合成棘白菌素B衍生物,是β-葡聚糖合成酶抑制剂,对念珠菌属、曲霉菌属有广泛抗菌作用。
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Micafungin (MCFG) is an echinocandin antifungal agent that exhibits potent activity against most species of Candida and Aspergillus. 米卡芬净（MCFG）是棘白菌素类抗真菌剂，具有强大的活动对大多数种类的念珠菌和曲霉。 - 2
We started administration of sulfamethoxazole and trimethoprim, ciprofloxacin hydrochloride, and micafungin sodium therapy as well as gamma-globulin. 我们给予复方新诺明、盐酸环丙沙星和米卡芬净以及丙种球蛋白进行治疗。 - 3
Newly available drugs include those in the echinocandin class, including caspofungin, micafungin, and anidulafungin, as well as the newer generation triazoles, voriconazole and posaconazole. 新药物包括棘白菌素类卡泊芬净、米卡芬净和阿尼芬净，以及新一代三唑类伏立康唑和泊沙康唑。
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