All rats were randomly divided into six groups: KXZZ high-does group, KXZZ middle-does group, KXZZ low-does group, valproate magnesium group, model group and normal control group.

Phlebitis in the control group using 50%magnesium sulfate wet, Observation group magnesium sulfate wet at the same time using TDP hyperthermia.

Treatment group decoct soup daily on the basic treatment of Western medicine, the control group use potassium-magnesium aspartate injection.