Quantitative RT PCR method were used to detect the mRNA levels of multidrugresistancegene in 32 leukemia children.
应用逆转录PCR结合同位素定量分析,对32例儿童白血病患者的多源耐药基因表达水平进行了研究。
2
An excessive expression of multidrugresistancegene is recently considered to be one of the reasons that lead to the failure of chemotherapy probably in childhood leukemias.
多源耐药基因的过度表达是导致白血病化学药物治疗失败的主要原因之一。
3
Objective To study the drug resistance in different types of acute leukemia in children, the expression of multidrugresistancegene and apoptosis-related genes were analyzed.