Objective: to discuss the evolution that apply microbiologicalassay to examine the quality of antibiotics.
目的：分析微生物检定法在抗生素质控分析中的应用进展。
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Methods Physicochemical analysis, pharmacological test, thin-layer examination, microbiologicalassay and observation of clinical verification were used to carry out systematic study.
方法采用理化分析、药理试验、薄层析检查、微生物测定、临床验证观察等方法进行系统研究。
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Results:Application of the microbiologicalassay is greatly receding in quantity analysis of antibiotics.