It is most likely that cholesterol and bile acid hyposecretion make the AKR strain susceptible to the development of fatty livers and resistant to gallstone formation.
肝内胆汁中胆固醇和胆酸的低分泌可能与akr鼠脂肪肝的发生和胆囊结石的免患性有关。
2
Conclusions The lithogenic diet as an environmental challenge unmasked phenotypes of mRNA expression of hepatic cholesterol metabolism regulatory enzymes of C57L and AKR mice.