医药科学

• 肢端感觉异常

  Many cell types are affected, including renal epithelial cells, myocardial cells and neuronal cells, endothelial cells, pericytes, and vascular smooth muscle cells, leading to angiokeratoma, acroparesthesias, and vascular disease of the heart, kidneys, and brain.

  引起诸多临床表现，如皮肤血管角质瘤，肢端感觉异常以及心脑肾的血管病变等，其中心肌受累也较为常见。 且为导致死亡的常见原因。