Finally, phagocyte precursors may undergo malignant transformation, which results in acute or chronic myelogenous leukemia.

Acute myelogenous leukemia (AML) is a cancer of the blood and bone marrow - the spongy tissue inside bones where blood cells are made.

Acute lymphocytic leukemia and acute myelogenous leukemia are each composed of blast cells, known as lymphoblasts or myeloblasts.