In earlier studies, the team found that insulin-likegrowthfactorbindingprotein-3 (IGFBP-3) binds Humanin and tempers its effects on promotion of cell survival.
Objective: to investigate plasma levels of insulinlikegrowthfactor 1 (IGF 1) and its bindingprotein3 (IGFBP 3) in type 2 diabetes and their relationship with microangiopathy.