It was little known at that time and the extensive ethical and methodological rules governing modern drug trials did not exist.
当时这种药物鲜为人知,同时也没有像现代药品试用管理中广泛制定的道德上和使用上的规则。
2
That is to say, when the rules governing authority have broken down in times of crisis, and that was certainly true in Hobbes' time, a time of civil war and crisis.