Conclusion the dissolution rate of tramadolhydrochloride tablets from different manufacturers were remarkably different, dissolution measurement is needed for controlling the quality.
结论不同厂家生产的盐酸曲马多片的溶出度明显不一致，进行溶出度检查有助于控制质量。
2
OBJECTIVE: To study the clinical pharmacokinetics and relative bioavailability of two kinds of tramadolhydrochloride sustained-released tablets.
目的：研究两种盐酸白马多缓释片的药代动力学及相对生物利用度。
3
METHODS Different particle size of tramadolhydrochloride, viscosity grades and the amount of HPMC, additive content and process were used to prepare tramadolhydrochloride sustained release tablets.