Objective: To establish a Rana catesbeiana alveolarmembrane model and to investigate the pulmonary absorption characteristics of insulin using this model.
目的：建立离体牛蛙肺泡膜模型并初步探讨胰岛素的肺吸收机制。
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At the end of the study, the rats were killed, ACE activity in serum and lung homogenate was assayed, and the alveolar-capillary membrane was observed by transmission electron microscope.
In one case, the major pathological changes of autopsy lung tissue were diffuse alveolar damage, hyaline membrane formed and alveolar exudative inflammation.