Plant could repair DNA damage induced by UV-B through many methods, mainly included light-repair, base excision repair, nucleotide excision repair and recombination repair etc.

AIM: To investigate the expression of nucleotide excision repair gene ERCC1 and its relationship with PAH (polycyclic aromatic hydrocarbons) -dna adducts in lung cancer tissues.

We focused on several key pathways, including nucleotide excision repair, drug transport and metabolism. Both expression and germline DNA variation were evaluated in these key pathways.