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单词 mitogen
释义

Definition of mitogen in English:

mitogen

noun ˈmʌɪtədʒ(ə)nˈmīdəjən
Physiology
  • A substance that induces or stimulates mitosis.

    〔生理〕促丝分裂原,促细胞分裂素

    Example sentencesExamples
    • In vitro tests of immune function in avian wildlife include proliferation of lymphocytes in response to various mitogens and phagocytosis of fluorescent particles by monocytes.
    • Cells from each individual were tested at 3 different concentrations of the mitogens for optimum stimulation.
    • The technique of three-color flow cytometry was used to generate precise estimates of cytokine responses to cells collected from the blood, cultured and stimulated with a mitogen.
    • Platelet-derived growth factor is a major polypeptide growth factor found in human serum, platelets and fibroblasts and is a potent mitogen for cells of mesenchymal origin.
    • Pokeweed mitogen stimulates both T and B cells.

Derivatives

  • mitogenic

  • adjective
    Physiology
    • When associated with vesicles of dipalmitoylphosphatidylcholine, surfactant protein C inhibited the mitogenic effect of lipopolysaccharide to a macrophage cell line.
      Example sentencesExamples
      • In addition, muscarinic receptor stimulation augmented the mitogenic responses of human airway smooth muscle cells to epidermal growth factor.
      • However, the patients despite their symptoms were all living independently and had normal proliferative responses to mitogenic stimulus and to purified protein derivative.
      • Mast cells produce basic fibroblast growth factor, which is a potent mitogenic factor for proliferation of smooth muscle cells, myofibroblasts, and fibroblasts.
      • Endothelin - 1 has been implicated in pulmonary hypertension because of its dual vasoconstrictor and mitogenic actions.

Origin

1960s: from mitosis + -gen.

Definition of mitogen in US English:

mitogen

nounˈmīdəjən
Physiology
  • A substance that induces or stimulates mitosis.

    〔生理〕促丝分裂原,促细胞分裂素

    Example sentencesExamples
    • Pokeweed mitogen stimulates both T and B cells.
    • Platelet-derived growth factor is a major polypeptide growth factor found in human serum, platelets and fibroblasts and is a potent mitogen for cells of mesenchymal origin.
    • In vitro tests of immune function in avian wildlife include proliferation of lymphocytes in response to various mitogens and phagocytosis of fluorescent particles by monocytes.
    • The technique of three-color flow cytometry was used to generate precise estimates of cytokine responses to cells collected from the blood, cultured and stimulated with a mitogen.
    • Cells from each individual were tested at 3 different concentrations of the mitogens for optimum stimulation.

Origin

1960s: from mitosis + -gen.

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更新时间:2025/1/31 2:37:33