单词 | 阿尔茨海默氏病 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
释义 | 阿尔茨海默氏病 —Alzheimer's diseaseless common: senile dementia 阿尔茨海默病 —Alzheimer's diseasesenile dementiaSee also:阿尔茨海默—Alois Alzheimer (1864-1915), German psychiatrist and neuropathologist
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更严重的损害可能指向老年痴呆症和阿尔茨海默氏病 , 它 涉及到的其他认知能力的丧失,如学习,推理,决策和注意。 cn.iherb.com | More serious impairment may point to [...] Dementia and Alzheimer's disease, which involves loss [...]of other cognitive abilities, such [...]as learning, reasoning, decision making and attention. iherb.com |
阿尔茨海默氏病国际组织的 Jan Killeen 着重指出阿尔茨海默氏病和相 关类型的痴呆与年龄歧视之间的联系。 daccess-ods.un.org | Jan Killeen of Alzheimer’s Disease International highlighted the linkages between Alzheimer’s disease and related types of dementia and age discrimination. daccess-ods.un.org |
老年性黄斑变性是发达国家导致失明的主要原因,其流行程度 是阿尔茨海默氏病 的 两 倍,影响到全世界大约3000万人。 tipschina.gov.cn | Age-related macular degeneration is a leading cause of blindness in the [...] developed world, and is twice as [...] prevalent as Alzheimer's disease, affecting approximately [...]30 million people worldwide. tipschina.gov.cn |
它还感到关切的是,保健专业人员并未接受足够的、关于如何护理痴 呆症和阿尔茨海默氏病患者 的培训,而且,公众对这些疾病的认识和理解也不 够。 daccess-ods.un.org | It is also concerned that health-care professionals do not receive sufficient training in relation to the care of persons [...] suffering from dementia [...] and Alzheimer’s and that there is a lack of awareness and understanding of the diseases among the public [...](art. 12). daccess-ods.un.org |
(a) 针对医生和保健专业人员,执行培训计划,介绍缔约国的《公约》义 务,以及痴呆症和阿尔茨海默氏病的 预 防和治疗 daccess-ods.un.org | (a) Training programmes for doctors and health-care professionals about the State [...] party’s Covenant obligations, as well as with regard to the prevention [...] and treatment of dementia and Alzheimer’s diseases daccess-ods.un.org |
确认精神和神经失常,包括 阿尔茨海默氏病 , 是一大病因,增加了全球非传 染性疾病负担,为此需要提供可公平享有的有效方案和保健干预措施的机会 daccess-ods.un.org | Recognize that mental and neurological [...] disorders, including Alzheimer’s disease, are an important cause of morbidity and [...]contribute to the global [...]non-communicable disease burden, for which there is a need to provide equitable access to effective programmes and health-care interventions daccess-ods.un.org |
Killeen 女士首先回顾说 9 个 65 岁以 上的人中就有 1 个人患有阿尔茨海默氏病,其 中大多数为妇女。 daccess-ods.un.org | Ms. Killeen started by recalling that 1 person in 9 over the [...] age of 65 has Alzheimer’s disease, the majority of [...]them being women. daccess-ods.un.org |
在 2011年 [...] 欧洲志愿服务之际,KANIKA集团公司创办了Ithaki的的慈善组织,一个以教育塞浦路斯公众对预防和治 疗阿尔茨海默氏病 为 宗 旨的非营利性组织。 kanikadevelopments.com | On the occasion of the European Year of Volunteering 2011, the KANIKA Group of Companies founded the Ithaki Charity Organization, a non-profit organization [...] with the purpose of educating the Cypriot public on matters concerning the [...] prevention and treatment of Alzheimer's disease. kanikadevelopments.com |
下列小组成员发了言:世界卫生组织(世卫组织)老龄化和生命周期司司长 John Beard、人权高专办特殊程序司经济、社会和文化权利科科长 Mara Bustelo 和阿尔茨海默氏病国际组织的 Jan Killeen。 daccess-ods.un.org | Presentations were made by the following panellists: John Beard, Director, Department of Ageing and Life [...] Course, World Health [...] Organization (WHO); Mara Bustelo, Chief, Economic, Social and Cultural Rights Section, Special Procedures Division, OHCHR; and Jan Killeen, Alzheimer’s Disease International. daccess-ods.un.org |
加龄医学研究所老年医学领域的古川胜敏准教授、荒井启行教授等基于PET淀粉样蛋白成像“BF-227”的探头,成功取得 了阿尔茨海默氏病 的 老年斑的体内成像,而基于本次与信州大学的池田修一教授们的共同研究,使用相同的“BF-227”,对于患有别样甲状腺素淀粉样蛋白沉积的系统性淀粉样变的患者心肌,成功综合成像。 tohoku.ac.jp | This research group, in collaboration with a research group led by Professor Shu-ichi Ikeda at Shinshu University, has successfully visualized accumulation of transthyretin, another kind of amyloid, in the myocardium of patients with systemic amyloidosis, also using BF-227. tohoku.ac.jp |
在美国,作为《美国复苏与再投资法案》的组成部分,国家 [...] 老龄问题研究所收到了分配给国家健康研究所资金中的大约 2.75 亿美元,用于 开展对阿尔茨海默氏病、营 养、肥胖症、骨质疏松症和心血管病及保健体系利用 [...] 率、健康方面的差异等的研究工作,以及用于支助家庭照护者。 daccess-ods.un.org | In the United States, as part of the American Recovery and Reinvestment Act, the National Institute on Ageing received approximately $275 million of the funding allocated to the National Institutes [...] on Health to conduct research on [...] such issues as Alzheimer’s disease, nutrition, obesity, [...]osteoporosis and cardiovascular [...]disease, as well as health utilization, health disparities and support for family caregivers. daccess-ods.un.org |
在一些最严重的情况下,例如,当老年人患有痴呆症 、 阿尔兹 海默氏症或 帕金森症时,他们可能忘记吃饭或不会自己吃饭。 daccess-ods.un.org | In some of the most dramatic situations, such as when the elderly suffer from dementia, Alzheimer’s or Parkinson’s disease, they may forget or be unable to feed themselves. daccess-ods.un.org |
有研究表明,脑源性神经营养因子与学习记忆能力密切相关, 在阿尔茨海默病 神 经 元的修复及结构重建中起着重要作用。 chinese.eurekalert.org | Brain-derived neurotrophic factor is associated with [...] learning and memory ability and plays an important role in the repair and [...] reconstruction of neurons in Alzheimer’s disease. chinese.eurekalert.org |
一些直接与年龄有关 的疾病,例如阿尔茨海默氏症或 帕金森氏症是导致老年人残疾的主要原因。 daccess-ods.un.org | Some diseases directly related to old age, such as Alzheimer’s [...] or Parkinson’s disease, are leading causes of disability among older persons. daccess-ods.un.org |
Federico Palermiti : 我们将通过每年在摩纳哥放映一部关 于阿尔茨海默氏 症 的影片,继续努力提高全民认知。 luxe-immo.com | Federico Palermiti : We continue our efforts to raise awareness by showing a film [...] every year in Monaco that [...] deals with Alzheimer's. At the screening members of the public are welcome to talk to specialists like Professor Alain Pesce, Vice-President [...]of AMPA, who attends [...]to explain aspects of the disease to people who want to know. luxe-immo.com |
当前,阿尔茨海默病主要 是依靠认知能力的改变以及排除其他会导致这些改变的病因后诊断的。 labtestsonline.org.cn | Alzheimer's disease is currently diagnosed based on [...] cognitive changes and by ruling out other causes of these changes. labtestsonline.org |
这是一项重大的研究成果。新研发的这种成像技术可以更好地协助临床诊断,并 使多个领域内的研究成为可能,包括神经退行性疾病(如帕金森氏症 和阿尔茨海默氏 症 ) 和心 脏 病 研 究。 australiachina.com.au | This is a significant outcome for research, as novel imaging techniques were developed for better clinical diagnosis, and investigation became [...] available to several research areas, including [...] neurodegenerative diseases such as Parkinson’s, Alzheimer’s and heart diseases. australiachina.com.au |
雌激素与神经细胞中的雌激素受体结合后,可减少淀粉样β蛋白的沉积并拮抗其细胞毒性作用, 对阿尔茨海默病 具 有潜在的治疗作用。 chinese.eurekalert.org | Estrogen binding of estrogen receptors in nerve cells can reduce amyloid β [...] protein deposition and antagonize its cytotoxic [...] effects in Alzheimer’s disease, providing a potential [...]therapeutic effect. chinese.eurekalert.org |
以Agilent [...] Technologies为例,这家世界领先的测量组织与UTS科学院携手合作,研发出世界第一台生物成像设备,将科技转化成成像技术,有助于临床诊断并能有效研究药物 对 阿尔茨海默 和 帕 金森等 疾 病 的 功 效。 australiachina.com.au | One such example is Agilent Technologies, a world-leading measurement organisation collaborating with UTS Science to produce a world first bio-imaging facility, which developed technologies into imaging techniques that have assisted clinical diagnosis and [...] allowed investigation of [...] effect of drugs on a range of diseases, including Alzheimer’s and Parkinson’s. [...]This relationship has [...]had significant benefits for both partners. australiachina.com.au |
政府的应对措施注重各种问题,包括药 品补贴、免除使用费、医疗保险计划、特殊服务,包括专门针对老人的部门,专 [...] 注一些慢性疾病、人员培训以及研究和政策,以应对心理健康问题,特别是老年 痴呆症,尤其是阿尔茨海默病。 daccess-ods.un.org | Government responses have focused on various issues, including subsidies for medicines, user fee exemptions, health insurance schemes, special services, including geriatricspecific departments, focused attention on certain chronic diseases, training of [...] personnel and research and policies to address mental health issues, notably dementia and, [...] specifically, Alzheimer’s disease. daccess-ods.un.org |
实际上,老龄化过程仍然受制 [...] 于下列因素:动脉粥化血栓形成的血管并发症所造成的主要疾病负荷;癌症相当 高的发病率;自发性帕金森氏病、阿 耳 茨海默氏病 和 其 他形式的痴呆症的普遍发 生。 daccess-ods.un.org | In fact the aging process is still hampered by a major [...] disease load due to the [...] vascular complications of atherothrombosis; by a considerably [...]high incidence of cancer; and by the prevalence of idiopathic Parkinsonism, Alzheimer’s disease and other forms of dementia. daccess-ods.un.org |
此前FDA已批准了数种用于治疗轻度 阿尔茨海默病 的 药物,多为胆碱酯酶抑制剂,但都未能从根本上治愈,且基本上是针对中早期患者。 chinese.eurekalert.org | USA. Food and Drug Administration has previously [...] approved many drugs for the treatment [...] of mild Alzheimer's disease, most of which belong [...]to cholinesterase inhibitors and [...]have failed to fundamentally cure. chinese.eurekalert.org |
有研究指,黃薑配合維生素D,有助於防 止 阿 爾 茨海默氏 症 (老年癡呆症)。 sfgourmet.com | Research found that turmeric with vitamin D helps prevent Alzheimer's disease (Alzheimer's disease). sfgourmet.com |
大量数据提示,RAGE参与阿尔茨海默病 的 发 病机制,Aβ与血脑屏障(BBB)或神经元细胞或微胶质细胞上RAGE的持续相互作用是淀粉样蛋白斑块形成和慢性神经元功能障碍的重要元素。 sharesinv.com | Substantial data suggest that RAGE is involved in the pathogenesis of Alzheimer’s disease, and that sustained Aβ interaction with RAGE at the blood-brain barrier (BBB), or in neuronal or microglial cells, is an important element of amyloid plaque formation and chronic neural dysfunction. sharesinv.com |
近期一项双盲临床试验中,18个月期间采集的数据显示,TTP488可延缓轻中 度阿尔茨海默病 患 者 的认知减退。 sharesinv.com | In a recent double-blind clinical trial [...] where data was taken over 18 months, TTP488 slowed cognitive decline in [...] patients with mild to moderate Alzheimer’s disease. sharesinv.com |
然而,这一大脑区域的刺激,是一个可靠的技术提高工作记忆10,增加记忆任务中的表现 在阿尔茨海默病 9 和 显 着降低线索挑起的吸烟渴求,例如35;因此它也是可以想象的,这可能是一个有用的策略来调节与慢性疼痛患者的疼痛处理相关的情感情感认知网络。 jove.com | Nevertheless, stimulation of this brain area is a reliable technique for enhancing working [...] memory 10, increasing performance on memory [...] tasks in Alzheimer disease9 and reducing cue-provoked [...]smoking craving significantly35 [...]for instance; therefore it is also conceivable that this might be a useful strategy to modulate affective-emotional cognitive networks associated with pain processing in patients with chronic pain. jove.com |
這些研究專案包括仿生眼、碳的捕捉 、 阿 爾 茨海默氏病 (Alzheimer’s )、柏金遜病 (Parkinson’s)和精神分裂症的治療方法以及突破性技術的研究,例如世界首創的千萬億位元組資料存儲技術 ——你能想像一萬張DVD所含的全部資料能被存儲於一張光碟內嗎? studyinaustralia.gov.au | Projects like the development of a bionic eye; carbon capture solutions; treatments for Alzheimer’s, Parkinson’s and schizophrenia; and technological breakthroughs such as the world’s first petabyte data storage technology – can you imagine 10,000 DVDs worth of material on just one disc? studyinaustralia.gov.au |
Jacques Touchon : 随着Bruno Vellas教授2008年名为阿尔茨海默氏症临床实验(CTAD)大会的成立,其重点为针 对阿尔茨海默氏 症 , 试验方法和新的药物治疗试验的临床试验。 luxe-immo.com | Jacques Touchon : With [...] Professor Bruno Vellas we set up a congress in 2008 called Clinical Trials on Alzheimer's Disease (CTAD) which focuses on therapeutic trials targeting Alzheimer's, the [...]methodology of the trials and new medication. luxe-immo.com |
AAD-2004是一种具有清除自由基和PGE2的双重药效药品,后者是引 发阿尔茨海默病 ( Al zheimer's disease)(AD)、帕金森氏症(Parkinson's disease)(PD)和肌萎缩性脊髓侧索硬化症(amyotrophic [...] lateral sclerosis)(ALS)等疾病的神经损伤的关键介体。 tipschina.gov.cn | Ltdhas begun dosing in the Phase 1 clinical testing of AAD-2004AAD-2004 was developed as a dual function drug to remove free radicals [...] and PGE2, the key [...] mediators of nerve injury in Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral [...]sclerosis (ALS)The [...]Phase 1 clinical trial was initiated to evaluate the safety, tolerability, and pharmacokinetics of AAD-2004 in healthy volunteers in April, 2010The first two cohorts of the clinical study have been successfully completed without serious adverse events. tipschina.gov.cn |
目前认为,阿尔茨海默病患者脑细胞内存在的过量淀粉样β肽与淀粉样β肽相关乙醇脱氢酶结合,干扰了细胞内正常氧化还原过程,导致线粒体肿胀、神经元死亡。 chinese.eurekalert.org | It is now considered binding of [...] excessive amyloid β peptide (Aβ) to amyloid β peptide [...]binding alcohol dehydrogenase (ABAD) [...]in the brain cells of Alzheimer’s disease patients hinders the normal intracellular redox process, leading to mitochondrial swelling and neuronal death. chinese.eurekalert.org |
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