| 单词 | 致癌性 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 释义 | 致癌性 noun —carcinogenicity n致癌性 adjective —carcinogenic adjSee also:致癌 n—carcinogenicity n • carcinogen n • oncogenic n 致癌—carcinogenic • cause cancer 癌性 n—carcinogenicity n 癌性 adj—cancerous adj
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在已進行的風險評估研究中，最重要的一項是氨基甲酸乙酯對小鼠 致癌性的毒理學研究。 cfs.gov.hk | The pivotal toxicological study for risk [...] assessment was a carcinogenicity study of EC [...]in mice. cfs.gov.hk |
(d) 旨在进一步澄清有关下列问题的标准的各项修正：高压气体；严重毒性； 生殖细胞突变性；致癌性；生 殖毒性及水生毒性 daccess-ods.un.org | (d) Miscellaneous amendments intended to further clarify the criteria for [...] gases under pressure; acute toxicity; germ cell [...] mutagenicity; carcinogenicity; reproductive [...]toxicity; and aquatic toxicity daccess-ods.un.org |
鑒於人力事務委員會部分委員曾就應否把良性及 非 致癌性間 皮瘤納入補償範圍的一般政策提出關注，議員可考慮應否成立法案委 [...] 員會研究有關事宜。 legco.gov.hk | In view of the concerns of some members of the Manpower Panel about the general policy [...] of whether compensation should cover [...] both benign and non-cancerous mesothelioma, member [...]may wish to consider whether to set [...]up a Bills Committee to examine relevant issues. legco.gov.hk |
食物含 有氨基甲酸乙酯引起對健康的關注是因為 其 致癌性。 cfs.gov.hk | The health concern of EC in food is [...] related to its carcinogenic potential. cfs.gov.hk |
衞生署 和 藥劑業及毒 藥 管 理局一直 留 意 任 何 新 藥 （ 包括 PPAR 促 效 劑 ） 用於老 鼠 和 人 類 身 上可能出現 的 致 癌 性 ， 並 因此要求藥 業公司在 申 請 註冊屬 於 PPAR 促 效 劑 的 藥 物 時 ， 須 另 就有關藥 物 在 老 鼠 身 上進行致癌 性 研 究 ， 以 及 其 後 在 人 體 進行臨床測 試 ，提交報 告 予 藥劑業及毒 藥 管 理局考慮。 legco.gov.hk | The DH and the PPB have always been aware [...] of possible carcinogenicity of any new drug, including PPAR agonists, in rodents and humans, and have therefore been requesting drug companies, in seeking registration of drugs belonging to the PPAR agonist class, among others, to provide reports on rodent carcinogenicity study and subsequent [...]clinical trials [...]on humans for consideration by the PPB. legco.gov.hk |
一九九四年，國際癌症研究機構曾評估丙烯酰胺 的 致癌性 ， 考 慮到 雖有足夠證據證明丙烯酰胺會令實驗動物患癌，但令人類患癌的證據卻 [...] 不足，因此把丙烯酰胺評定為第 2A 組，即可能令人類患癌。 cfs.gov.hk | In 1994, International Agency [...] for Research on Cancer (IARC) evaluated [...]acrylamide and considered that there was sufficient [...]evidence of carcinogencity in experimental animals but inadequate evidence of carcinogenicity in humans and classified it as Group 2A (probably carcinogenic to humans). cfs.gov.hk |
尽管烯烃硫化物尚未进行过致癌性研 究测试，但相关的基因毒性研究显示，它们并不会产生致癌危害。 cn.lubrizol.com | While olefin sulfides have not been tested in carcinogenicity studies, the genotoxicity studies indicate that they do not pose a carcinogenic hazard. lubrizol.com |
基於在研 究 之 中 ， 老 鼠 身 上出現 [...] 腫瘤的 比率，令人關 注 到 人 類 長 期 服 用 會 產 生安全問題， 因此 研 究建議屬於 PPAR 促 效 劑 的 藥 物，必須先 在 [...] 老 鼠 身 上進行最少 兩 年的致 癌 性 研 究 ， 然 後才可在人 體 進行臨床研 究 。 legco.gov.hk | The study recommended that due to the prevalence of tumor found in rodents during that study, and hence safety concern about long-term use of such substances on humans, rodent carcinogenicity study for at least [...] two years should be done for drugs [...] belonging to the PPAR agonist class prior to the [...]conduct of clinical studies on humans. legco.gov.hk |
但部分委員認為，該建議的保障範圍 不應只限於惡性間皮瘤，而是應包括良性及 非 致癌性 間 皮 瘤個案。 legco.gov.hk | Some members, however, considered that the coverage of the proposal [...] should not be confined to malignant mesothelioma and cases of [...] benign and non-cancerous mesothelioma should [...]be included. legco.gov.hk |
世界衞生組織轄下的國際癌症研究機構 於 1999 年將十溴聯苯醚列為第 3 [...] 類物質(即在會否令人類患癌方面未能分 類的物質)，但並沒有就五溴聯苯醚及八溴聯苯醚 的 致癌性 進 行 評估。 cfs.gov.hk | The International Agency for Research on Cancer (IARC) of the [...] World Health Organization in 1999 classified DecaBDE in Group 3 (i.e. not [...] classifiable as to its carcinogenicity to humans). cfs.gov.hk |
尽管ZDDP尚未进行过致癌性研究测试，但是基因毒性研究和配制产品研究结果均表明它们不属于致癌物。 cn.lubrizol.com | While ZDDPs have not [...] been tested in carcinogenicity studies, genotoxicity [...]studies and studies of formulated products indicate [...]that they are not carcinogenic. lubrizol.com |
不過，近期有體外 研究指出，多溴聯苯醚會誘發氧分子活化，可能破壞脫氧核糖核酸。2在 [...] 缺乏人體數據的情況下，加上只有零星證據證明這類物質會令動物患 癌，世界衞生組織轄下的國際癌症研究機構於 1999 年把十溴聯苯醚列為 第 3 類物質( [...] 即在會否令人類患癌方面未能分類的物質)，但並沒有就五溴 聯苯醚和八溴聯苯醚的致癌性進行 評估。 cfs.gov.hk | But recent in vitro studies indicated that PBDEs can cause DNA damage through the induction of reactive oxygen species.2 Based on the lack of human data and the limited evidence of carcinogenicity in animals, the International Agency for Research on Cancer (IARC) of the [...] World Health Organization in 1999 classified DecaBDE in Group 3 (i.e. not [...] classifiable as to its carcinogenicity to humans). cfs.gov.hk |
由于我们关注的是潜在致癌性，而有些PAHs会破坏细胞内的基因物质，因此不可能厘定一个全无风险的摄入量。 cfs.gov.hk | Since cancer-causing potential is the [...] concern and that some PAHs can damage genetic materials inside cells, it is not possible [...]to define a level of exposure which is without risk. cfs.gov.hk |
上述结果说明烷基芳基磺酸盐无 致癌性。 cn.lubrizol.com | Based on these results, they are not [...] expected to be carcinogenic. lubrizol.com |
食物含有氨 基甲酸乙酯引起關注與氨基甲酸乙酯 的 致癌性 有 關。 cfs.gov.hk | The concerns of EC in foods on public health was [...] relating to its carcinogenic potential. cfs.gov.hk |
二 零 零 一 年 ， 联 合 国 粮 食 及 农 业 组 织 ∕ 世 界 卫 生 组 织 联 合 食 物 添 加 剂 专 家 委 员 会 (JECFA)( 下 称 “ 专 家 委 员 会 ” ) 指 出 ， [...] 根 据 现 有 的 流 行 病 学 和 临 床 资 料 ， 不 足 以 计 算 [...] 赭 曲 霉 毒 素 A 的 人 类 致 癌 性 ， 而 引 致 区 域 性 巴 尔 [...]干 半 岛 肾 病 变 的 因 素 亦 可 能 包 括 其 他 肾 毒 物 17 。 cfs.gov.hk | The Joint FAO/WHO Expert Committee on Food Additives (JECFA) concluded in 2001 that the epidemiological and clinical data [...] available do not provide a basis for calculating [...] the likely carcinogenic potency in human [...]and that Balkan Endemic Nephropathy may [...]involve other nephrotoxic agents. cfs.gov.hk |
2016年1月前，有毒物質管制部將列出若干產品作為優先產品，這些產品必須是使用了1種或以上的相關化學品，而該化學品亦須符合以下兩項準則：(i)在7種危害特 徵 ( 致癌性 、 生殖 毒 性 、 致 突變性、發育毒性、內分泌干擾、神經毒性和/或持久性生物累積性毒性) 中含有1種或以上因而列入法例指定清單的化學品；及(ii)列入水質、空氣質素或生物監測規例內的曝露指數清單的化學品。 prorsumgroup.com | Prior to January 2016 DTSC would list a product as a priority product only if the product is being listed on the basis of one or more chemicals of concern that meet both of two criteria: (i) the chemical is listed on the list of lists specified in the regulations because it exhibits one or more of seven hazard traits (carcinogenicity, reproductive toxicity, mutagenicity, developmental toxicity, endocrine disruption, neurotoxicity and/or persistent bioaccumulative toxicity); and (iii) the chemical is listed on one of the exposure indicator lists identified in the regulations for water quality, air quality or biomonitoring. prorsumgroup.com |
有關公司為這兩種 藥 物 向 藥劑業及毒 藥 管 理局提出 申 請 註冊前 ， 已 [...] 就這兩種 藥 物 在 老 鼠 身 上進行為期 兩 年的致 癌 性 研 究 ， 其 後 也在人 體 進行臨床測 試 。 legco.gov.hk | Both Avandia and Actos had been [...] subject to two-year carcinogenicity studies on rodents [...]and subsequent clinical trials on [...]humans before their registration applications were tendered to the PPB for consideration. legco.gov.hk |
13. 1994 [...] 年，國際癌症研究機構評估丙烯酰胺 的 致癌性 ， 認 為有足夠證 據證明丙烯酰胺會令實驗動物患癌，但沒有足夠證據顯示丙烯酰胺會令 [...]人類患癌，所以把丙烯酰胺分類為第 2A組物質( 可能令人類患癌的物 質 )8。 cfs.gov.hk | The Centre for Food Safety (CFS) of [...] the Food and Environmental Hygiene Department [...](FEHD) conducted a risk assessment study [...]on the dietary exposure of acrylamide in Hong Kong adults, in parallel with the joint Consumer Council (CC) study titled “Acrylamide in Some Popular Foods” in 2010. cfs.gov.hk |
用作試驗的動物應考慮其對感染的抵抗力、壽命長短、自發腫瘤的頻率高 低以及對已知致癌原的敏感性等條件。 cmchk.org.hk | When selecting the test animals, factors which should be considered include: the animal’s resistance against [...] infectious disease, its life span, incidence of spontaneous tumor formation, [...] as well as its sensitivity to known carcinogens. cmchk.org.hk |
由於部分外源性激素已知可令人類 致癌 ， 國 際當 局一般會嚴格管制甚至禁止食物中出現這些外源性激素。 legco.gov.hk | As some exogenous hormones are found to be carcinogenic to humans, international [...] authorities usually exercise strict control [...]over or even prohibition of the occurrence of such exogenous hormones in foods. legco.gov.hk |
对无明确限量的一种致癌物质来说，JECFA 使用可获得的 摄入量数据与致癌潜力 数据来估算潜在的人口危 险 性。 codexalimentarius.org | For a carcinogen with no clear [...] threshold, JECFA uses available data on [...] intake combined with data on carcinogenic potency to estimate potential population risks. codexalimentarius.org |
有害废物对公共健康或环境构成严重或潜在 威胁，通常显示下列一个或多个特征 ： 致癌 、 易 燃、氧化、腐败、有毒、放 射性 和爆炸性。 daccess-ods.un.org | Hazardous waste is waste that poses substantial or potential threats to public health or the environment and [...] generally exhibits [...] one or more of these characteristics: carcinogenic, ignitable (i.e., flammable), oxidant, [...]corrosive, toxic, radioactive and explosive. daccess-ods.un.org |
動物實驗顯示氨基甲酸乙酯屬多位 點基因毒性致癌物質。 cfs.gov.hk | EC was considered a genotoxic multisite carcinogen in experimental animals. cfs.gov.hk |
考虑到 无机砷的致癌风险 ，大家应致力减少市民的无机砷摄入量。 cfs.gov.hk | Having considered the carcinogenic risk of inorganic [...] arsenic, efforts should be made to reduce the exposure to inorganic arsenic of the population. cfs.gov.hk |
将健康影响归因于电离辐射照射的能力；电离辐射照 射 致癌 风 险 估值的 不确定性；选 定的体内发射体对生物的影响 daccess-ods.un.org | The Committee considered that significant progress had been made on those documents and envisaged that the documents on the ability to attribute and on uncertainties could be finalized at the next session. daccess-ods.un.org |
有關各項安全性試驗，即包括重金屬及有毒元素含量測試、農藥殘留量 測試、微生物限度測試、急性毒性試驗、長期毒性試驗、局部 毒 性 試 驗 、 致突 變試驗、致癌試驗和生殖毒性試驗 的技術指引，請參看附錄一至九的說明。 cmchk.org.hk | For the details of technical guidelines for various product safety tests (including heavy metals and toxic element test, pesticide residues [...] test, microbial limit test, acute toxicity test, long term toxicity test, [...] local toxicity test, mutagenicity test, carcinogenicity test and reproductive and development [...]toxicity test), please refer to Appendix 1 - 9. cmchk.org.hk |
东北大学大学院医学系研究科放射性 同 位 素中心的本桥Hozumi准教授，与同医化学领域的光石阳一郎博士、田口惠子助教、山本雅之教授、东京大学先端科学技术研究中心的油谷浩幸教授、国立癌研究中心研究所癌基因组学研究领域的柴田龙弘领域长的研究小组，共同研究发现了 导 致癌 细 胞 恶化的代谢控制组织。 tohoku.ac.jp | Associate Professor Hozumi Motohashi at Center for Radioisotope Sciences, Tohoku University Graduate School of Medicine, Dr. Yoichiro Mitsuishi, Assistant Professor Keiko Taguchi, [...] and Professor Masayuki Yamamoto at [...] Division of Medical Biochemistry, Tohoku University Graduate School of Medicine, Professor Hiroyuki Aburatani at Research Center for Advanced Science and Technology, University of Tokyo, and Division Leader Tatsuhiro Shibata at the National Cancer Center have jointly discovered the metabolic control mechanism that drives the malignant evolution of cancer cells. tohoku.ac.jp |
4、新品种向食品中迁移水平为 5-60mg/kg，提供急性经口毒 性、三项致突变试验（Ames 试验、体外哺乳动物细胞染色体畸变试 验和骨髓细胞微核试验）、90 [...] 天大鼠亚慢性经口毒性、繁殖发育毒 性（两代繁殖和致畸试验）、慢性经口 毒 性 和 致癌 试 验 资料。 agrichina.org | (4) For new species from which the migration level into foods is between 5 and 60mg/kg, the following data should be provided: acute oral toxicity, three tests for mutagenicity (i.e., Ames test, In vitro mammalian cells chromosome aberration test, and micronucleus test of bone marrow cells), 90 days subchronic toxicity test in rats, [...] reproduction and development toxicity (two-generation and teratogenicity test), [...] chronic oral toxicity and7 carcinogenic test. agrichina.org |
利用有针对性的基因测定来对致癌基 因 和抑癌基因进行深度测序，以及利用外显子组测序来识别有助于个体癌症治疗的罕见或未知基因，肿瘤学家可以更好地识别病人肿瘤的深层成因，从而制定出一套目标性更强的治疗计划。 tipschina.gov.cn | Using targeted gene assays for deep sequencing of oncogenes and tumor suppressor genes, and exome sequencing to identify rare or unknown genes that may contribute to an individual's cancer, an oncologist can better identify the underlying cause of a patient's tumor to create a more targeted treatment plan. tipschina.gov.cn |
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