单词 | 甲基化 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
释义 | 甲基化 noun —methylation nExamples:氨基甲酸酯类化合物—carbamate See also:甲基 n—methyl n 甲基—methyl group (chemistry) 甲—armor plating • bladed leather or metal armor (old) • ranking system used in the Imperial examinations (old) • (of the fingers or toes) nail • (used for an unspecified person or thing) • civil administration unit (old) • shell or carapace • first (in a list, as a party a contract etc)
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患糖尿病的母亲的后代表现出了更高的畸形和死胎的发生率,Zhao-Jia Ge博士等人如今把它与母亲的印迹基因Pe g3 的 甲基化 被 削弱联系在了一起。 chinese.eurekalert.org | Offspring of diabetic mothers display a higher incidence of [...] malformations and fetal death, which Dr. Zhao-Jia Ge et al. now link [...] to impaired methylation of maternal imprinting gene Peg3. chinese.eurekalert.org |
来源似乎是被淡水及海洋水体沉积物中的微生物的生 物甲基化的无机汞(Clarkson 2002)。 zeromercury.org | The source appeared to be inorganic mercury biomethylated by microorganisms in sediments of both fresh and ocean water (Clarkson 2002). zeromercury.org |
核心组蛋白的乙酰化和甲基化可以 通过染色质的免疫沉淀确定。 labome.cn | Acetylation and methylation of core histones [...] can be determined by chromatin immunopercipitation. labome.com |
结合所有这些因素,对于由水生生 物生产、并累积、滞留的甲基汞, 甲基化 的 净 速度对其数量有强烈影响。 zeromercury.org | When all of these factors are combined, the net methylation rate can strongly influence the amount of methylmercury that is produced and available for accumulation and retention by aquatic organisms. zeromercury.org |
在这里,我们重点介绍识别蛋白质修饰的一般方法,质谱;识别磷酸化的特异性方法,磷酸盐标记;识别泛素化的方法;在染色质重塑过程中识别组蛋白乙 酰 化 和 甲基化 的 方法;识别蛋白质糖基化的方法(表1和图1B)。 labome.cn | Here we focus on the mass spectrometry as a general approach for identifying protein modification, and specifici methods for phosphorylation, such as orthophosphate labeling, for ubiquitination, for histone acetylation and methylation in the context of chromatin remodeling, and for protein glycosylation (Table 1 and Fig 1B). labome.com |
可抑制新合成 DNA 的甲基化,DNA 甲基化对测定细胞对组蛋白去乙酰酶抑制剂的凋亡敏感性是很重要的。 scbt.com | 5-Aza-2′-Deoxycytidine inhibits methylation of newly synthesized DNA by specifically inhibiting Dnmt. scbt.kr |
B, 翻译后修饰,作为细胞内信号(磷酸化),蛋白稳定性的调控(泛素),转录调控(组蛋白乙 酰 化 和 甲基化 ) ,细胞表面信号(糖基化)等多种多样的细胞功能中发挥重要作用。 labome.cn | B, Post-translational modifications play important roles in diverse cell functions as intracellular signaling (phosphorylation), regulation of protein stability (ubiquitination), regulation of transcription (histone acetylation and methylation), and cell surface signaling (glycosylation). labome.com |
这个低分子RNA,对相同领域的隐性SP11基因产 生 甲基化 诱 导,而后天性地抑制了隐性SP11基因性的表现。 tohoku.ac.jp | This siRNA [...] induced DNA methylation in homologous [...]regions of recessive SP11 alleles, and epigenetic controlled gene expressions. tohoku.ac.jp |
z 1953 年发生在日本水俣湾的一件悲惨且臭名昭著的事件,突出了无机汞作为水体污染物的危险性,该 [...] 事件中工业化乙醛生产的无机汞副产品直接排放入当地海湾,并被海湾底部厌氧污泥中的微生 物 甲基 化。 zeromercury.org | z A tragic and now infamous event which occurred in Minamata Bay - Japan in the 1953, highlighted the dangers of inorganic mercury as a water pollutant when organic mercury by-products of industrial-scale acetaldehyde [...] production were directly discharged in the [...] local bay and methylated by microorganisms [...]in anaerobic sludge lying at the bottom of the bay. zeromercury.org |
水生环境中的一些参数影响 汞的甲基化,从 而影响其生物放大作用。 zeromercury.org | Several parameters in the aquatic environment [...] influence the methylation of mercury and [...]thereby its biomagnification. zeromercury.org |
z 伴随全球气候变化的水位上升可能 也与汞的甲基化及其 在鱼体内的累积有关系。 zeromercury.org | z Rising water levels associated with global climate change may also have [...] implications for the methylation of mercury and [...]its accumulation in fish. zeromercury.org |
作者的结论是: 我们的结果表明,H1[组蛋白]作用和染色质紧密程度控制着多能Oct4基因的表观遗传,最可能透过 D N A 甲基化 和 组 蛋白修饰作出调控。 hongkongstemcell.com | Our results suggest a role of H1 [histone] and chromatin compaction in [...] epigenetic regulation of the [...] pluripotency gene Oct4, likely mediated through DNA methylation and histone [...]modifications. hongkongstemcell.com |
其中最重要的就 是汞甲基化细菌(如,硫酸盐还原剂 ) 甲基化 和 去 甲基化 的 速 度。 zeromercury.org | Of most importance are the rates of methylation and demethylation by mercury methylating bacteria (e.g., sulphate reducers). zeromercury.org |
体外研究表明2% ReGeniStem™ Red Rice可促进与衰老相关的基因启动子区CpG岛的 反 甲基化 , 即 使暴露于UVB下,也能使老化细胞的行为更像是年轻细胞;增强胶原蛋白生成和上调皮肤桥蛋白,进而能够紧致皮肤,改善皮肤的屏障保护功能。 cn.industrysourcing.com | In vitro treatment with 2% ReGeniStem™ Red Rice encourages the demethylation of CpG islands in the gene promoter regions despite exposure to UVB making the aged cells behave more like young cells, increases collagen production and upregulates dermatopontin expression which may be able to firm the skin and influence the skin barrier function especially in the dermis and epidermis. us.industrysourcing.com |
建立了亲水作用色谱(HILIC)测定组织中全基因组 D N A 甲基化 水 平 的方法。 chrom-china.com | A hydrophilic interaction liquid chromatographic (HILIC) method has been developed for the determination [...] of global DNA methylation in tissues. chrom-china.com |
两个系统都支持Illumina创新的遗传分析产品线,这些产品适用于基因分型、CNV分析、 D N A 甲基化 和 基因表达图谱分析。 illumina.com.cn | Both systems support [...] Illumina's broad portfolio of innovative genetic analysis assays for genotyping, CNV analysis, DNA methylation, and gene [...]expression profiling. illumina.com |
保守的核心组蛋白H2A,H2B,H3,和H4的表观遗传修饰(如磷酸化,泛素化,乙 酰 化 和 甲基化 ) 在基因表达中发挥重要的调节作用 [15] 。 labome.cn | Epigenetic modifications (such as phosphorylation, ubiquitination, acetylation and methylation) of the conserved core histones H2A, H2B, H3, and H4 play an important regulatory role in gene expression [15] . labome.com |
利用群体方法及最新的技术及资源,SNP [...] Genetics提供了全面的阵列型解决方案,适用于基因分型、拷贝数变异 、 甲基化 研 究 和基因表达谱分析。 illumina.com.cn | Using a population approach with state-of-the-art technologies and resources, SNP Genetics provides comprehensive array-based solutions for genotyping(GWAS, upto 384 SNP multiplex), next [...] generation sequencing(NGS), copy number [...] variations(CNV), methylation studies, gene [...]expression profiling and statistical analysis. illumina.com |
z 湖泊酸化,象硫这种刺激甲基化的物 质的加入,以及新近泛滥的水库或形成的湿地土壤中汞的动员说 明增加了汞成为鱼类中一大问题的可能性(USGS 2000)。 zeromercury.org | z Lake acidification, addition of substances like sulfur that stimulate methylation, and mobilization [...] of mercury in soils [...]in newly flooded reservoirs or constructed wetlands have been shown to increase the likelihood that mercury will become a problem in fish. zeromercury.org |
TCA处理之后的长达4个小时, 对包括fos基因启动子在内的3kb区域的组蛋 白 甲基化 状 态 进行了测定 [24] 。 labome.cn | Histone methylation within a 3kb region including the fos gene promoter is determined for up to 4 hours after TCA treatment [24] . labome.com |
天赐创新采用阳离子淀粉PQ-TCS 11(淀粉羟丙基三甲基氯化铵)与特种硅油的复配香波技术,使香波在 稀释早期即可形成絮胶,并有效包裹和运载特种硅油。 cn.industrysourcing.com | Tinci innovatively combines Cationic Starch [...] PQ-TCS 11 (INCI: STARCH HYDROXYPROPYL TRIMONIUM CHLORIDE) with special silicone [...]in shampoo system [...]which helps form coacervate at very early rinsing stage enhancing silicone deposition effectively. us.industrysourcing.com |
甲醇的其他常见名称包括甲基乙醇、甲基水合物、木 精、木醇和甲基氢氧化物。 methanex.com | Other common names for methanol include methyl alcohol, methyl hydrate, wood spirit, [...] wood alcohol, and methyl hydroxide. methanex.com |
Drieß博士在硅磷化合物和亚甲硅基等 硅有 机 化 学 领域的重要合成用分子链节方面做出了开创性工作, 开拓了科学知识领域”, 施陶迪格说。 wacker.com | Prof. Drieß’ pioneering work in the [...] field of silicon-phosphorus compounds and silylenes, which represent [...]promising synthetic building [...]blocks in organosilicon chemistry, has been trailblazing,” said Dr. Staudigl. wacker.com |
日本东京三菱化学株 式会社投建的高新聚合物工厂,主要生产 PTMG(聚四亚甲基醚二 醇)弹性纤维,大量供应于中国纺织市场。 emerson.com | Mitsubishi Chemical Corporation, Tokyo, Japan, is the majority owner of MCC Advanced Polymers (MAP), which will produce [...] PTMG fibers for use in China's textiles industry. emerson.com |
执行委员会审查了随同巴基斯坦体制建设项目第七阶段延长申请提交的报告,并赞 [...] 赏地注意到巴基斯坦实现了氟氯化碳、哈龙、四 氯 化 碳 、 甲基 氯 仿 和甲基溴的淘汰目标, 蒙特利尔议定书缔约方会议核准的重要用途进程下的氟氯化碳除外。 multilateralfund.org | The Executive Committee reviewed the report presented with the institutional strengthening project renewal request for Pakistan for Phase VII, and noted with appreciation the fact that Pakistan [...] achieved phase-out targets for CFCs, [...] halons, CTC, methyl chloroform and methyl bromide, except [...]for CFCs approved under the essential [...]use process by the Meeting of Parties to the Montreal Protocol. multilateralfund.org |
加拿大的包括圣卢西亚制冷和空调行业的消耗臭氧层物质的最终淘汰管理计划和乌拉 圭附件 A 第一类物质最终淘汰管理计划,意大利的是刚果民主共和国最终淘汰溶剂行业的 消耗臭氧层物质总体项目,摩洛哥淘汰用作土壤熏蒸剂 的 甲基 溴 , 在塞尔维亚最终淘汰四 氯化碳项 目;西班牙的是阿拉伯利比亚民众国淘汰园艺中 的 甲基 溴。 multilateralfund.org | For Canada, those covered the terminal phase-out management plan for ODS in the refrigeration and air-conditioning sector in Saint Lucia and the terminal phase-out management plan for Annex A Group I substances in Uruguay; for Italy, the umbrella project for terminal phase-out of ODS in the solvent sector in the Democratic [...] Republic of Congo, [...] the phase-out of methyl bromide as a soil fumigant in Morocco, and the terminal CTC phase-out project in Serbia; and for Spain, the phase-out of methyl bromide in horticulture [...]in Libyan Arab Jamahiriya. multilateralfund.org |
如果每個類別的食品和樣本數目增加 , 化 驗 檢 測工作便能 夠更全面地涵蓋香港市面供應的發酵食物,以及更準確地評估這些食物 的氨基甲酸乙酯含量範圍和平均值。 cfs.gov.hk | Increasing both the number of food items and the number of samples per individual food commodity for laboratory analysis could provide a more comprehensive coverage and a more precise estimate of the range and average EC concentration of fermented foods in the Hong Kong market. cfs.gov.hk |
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