| 单词 | 核苷 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 释义 | 核苷 —nucleosideExamples:核苷酸—nucleotide 脱氧核苷酸—deoxyribonucleoside monophosphate • dNMP See also:苷—glycoside • licoriceAE
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后来他开始领导EBI的序列数据库团队，并自2007年与Ewan Birney成为蛋白质和核苷酸数 据团队（PANDA）的联合主管。 tilsi.org | Later he has been leading the Sequence Database Group at EBI, and since 2007 he is Joint Head of the Protein and Nucleotide Data (PANDA) Group, together with Ewan Birney. tilsi.org |
约500 000个DNA功能模块的变种（单核苷酸多 态性，SNP，它们遍布DNA的整个长度，并被证明与某些生理和行为特征或疾病敏感性相关）正在接受常规分析。 project-syndicate.org | Already, variations in the composition of about 500,000 DNA building blocks [...] (SNPs or Single Nucleotide Polymorphisms), [...]spread over the total length of the DNA [...]and shown to correlate with particular physical and behavioral characteristics or susceptibility to diseases, are being analyzed routinely. project-syndicate.org |
Irina Pugach及其同事分析了澳大利亚、新几内亚、东南亚岛屿以及印度的原住民的全基因组 单 核苷 酸 多 态（SNP）数据。 chinese.eurekalert.org | Irina Pugach and colleagues analyzed [...] genome-wide single-nucleotide polymorphism [...](SNP) data from aboriginal Australians, New [...]Guineans, island Southeast Asians, and Indians. chinese.eurekalert.org |
烟酰胺腺嘌呤二核苷酸（ NADH），是脱氢酶的辅酶。 cn.iherb.com | Chronic Fatigue Syndrome (CFS) is defined as unexplained, persistent, or relapsing fatigue, with a definite beginning. iherb.com |
低‘短链碳水化合物’（可发酵的、 寡 核苷 酸 、二糖、单糖和多元醇）饮食”是由澳大利亚墨尔本莫纳什大学的营养学家 Sue [...] Shepard医生研发的一种治疗方法。 shanghai.ufh.com.cn | The FODMAP [...] (Fermentable, Oligo, Di, and Mono-saccharides [...]and Polyols) diet is a treatment approach researched and developed [...]by dietitian Dr. Sue Shepard at Monash University in Melbourne, Australia. beijing.ufh.com.cn |
家蚕与果蝇的ND2基因序列同源性约69.7%，COⅠ基因的同源性约83.8%，COⅡ基因5′端的同源性约80%，这表明细胞色素氧化酶基因在物种间比烟酰胺腺嘌呤 二 核苷 酸 脱氢酶基因保守。 actazool.org | The homology of ND2 gene sequence between Bombyx mori and Drosophila melanogaster is about 69.7%, while the homology of COⅠ and 5′end of COⅡ gene sequences between B.mori and D. melanogaster is about 83.8% and 80% respectively. actazool.org |
美丽小条鳅的Cyt b序列包含138个核苷酸变 异位点（占全序列12.11％）。 actazool.org | There were 138 variable nucleotide sites among 1140 base pairs of the Cyt b gene (12.11% of the full sequence). actazool.org |
公认的专利Smartbeam激光技术在蛋白质组织成像、整体蛋白质分析、生物制剂或 寡 核苷 酸 质量控制以及LC-MALDI蛋白质组学等工作流程提供无与伦比的分析和基质灵活性，并且在一级TOF和二级TOF/TOF模式下都能在1-1000赫兹频率下完成。 bruker.com | The well-established proprietary smartbeam laser provides unprecedented analytical and matrix flexibility in workflows from protein tissue imaging, intact proteins analysis, Glycoproteomics, biologics or oligo QC, to LC-MALDI proteomics - all fully enabled at 1-2000 Hz repetition rates. bruker.com |
因此，在 1999 年十家大型制药公司和英国的维康基金会 (Wellcome Trust) [...] 一起成立了一个协会64 ，发现 并绘制三十万个单核苷酸多态性 (SNP) 的图形65 。 iprcommission.org | Thus, in 1999, ten large pharmaceutical companies and the U.K. Wellcome Trust established a consortium64 to find and map 300,000 common SNPs.65 This has generated a widely [...] accepted, high-quality, extensive, publicly [...] available map using SNPs as markers evenly [...]distributed throughout the human genome, [...]many of which will be used to locate targets for drug research. iprcommission.org |
病毒粒子树树 700nm×11nm 的树状 体，包含一条树树的 RNA [...] 分子，树 RNA 分子由近 10000 个核苷酸树成，并包被在由多达 2000 [...]个树基构成的树一外壳蛋白中（García and Cambra，2007）。 ippc.int | The virus particles are flexuous rods of approximately 700 nm × 11 nm, and are composed of a [...] single-stranded RNA molecule consisting of [...] almost 10 000 nucleotides coated by up [...]to 2 000 subunits of a single coat protein (García and Cambra, 2007). ippc.int |
针对转染或基因治疗，通过优化至纳米颗粒及脂质体上的加载，改善DNA或 寡 核苷 酸 的传输及半衰期。 malvern.com.cn | Improve the delivery and half-life [...] of DNA or oligonucleotides for transfection [...]or gene therapy by optimizing their loading [...]onto nanoparticles and liposomes. malvern.com |
这个方法中最重要的一点就是方依赖了具有光活性 的 核 糖 核苷 类 似物，例如4-硫 尿 核苷 ， 在 活体细胞中将其插入到新生RNA转录本中。 labome.cn | The most critical point in this method is the use of photoreactive ribonucleoside analogs, such as 4-thiouridine (4-SU) into nascent RNA transcripts. labome.com |
为了进行硫代反义寡核苷酸药物FT19的质量控制研究,建立了用阴离子交换高效液相色谱(AX-HPLC)和毛细管凝胶电泳(CGE)分析自行合成的FT19有关物质的方法。 chrom-china.com | A method using anion exchange high performance liquid chromatography (AX-HPLC) and capillary gel electrophoresis (CGE) was established for the analysis of the related substances in phosphorothioate antisense oligonucleotide FT19 for quality control. chrom-china.com |
这幅图说明了双螺旋的几个机构特征：首先为右旋，双链以相反的方向运转 ； 核苷 酸 ， 即链的构成块，具有形成骨骼的一个部分和伸向螺旋中间的一个部分（碱基）；一个链中的内部伸向碱基相互对齐，因此能够与相反链中的碱基配对。 wdl.org | It illustrates several structural features of the double helix: it is right-handed, [...] with the two strands running in opposite [...] directions; the nucleotides, the building [...]blocks of the strands, have a part that [...]forms the backbone and a part (the base) that projects into the middle of the helix; and the internally projecting bases in one strand are aligned so that they can pair with a base from the opposite strand. wdl.org |
这个过程始于移去两条cDNA 3端的几个核苷酸。 labome.cn | The process begins with the removal [...] of several nucleotides from the 3’ [...]termini of both strands of cDNA. labome.com |
成熟的海巴戟果分离为50%的水乙醇溶液，经【3H】胸腺嘧 啶 核苷 分 析，证明能刺激BALB/C小鼠胸腺细胞；因而推测海巴戟果能抑制小鼠Lewis肺癌的作用机制部分是由於刺激T-细胞的免疫功能所致。 int-tm.com | Mature Morinda citrifolia fruit [...] is separated into 50% aqueous ethanol [...] solution, the [ 3H ] thymidine analysis, [...]shown to stimulate BALB/C mouse thymus cells; [...]therefore hypothesized that Morinda citrifolia fruit can inhibit mouse Lewis lung cancer mechanism is in part due to the stimulation of T- cells immune function by. en.int-tm.com |
美国人类基因科学公司于 2000 年 2 月因“多核苷酸编 码人类 G-蛋白质趋化因子受体 HDGNR10（现称为 CCR5）”而被授予编号为 No.6.025.154 的美国专利权，该专利权 范围宽泛，包括该基因及其所有的医学应用，诸如阻碍或提升该受体功能的治疗。 iprcommission.org | In February 2000, HGS was issued US patent No. 6,025,154 for “Polynucleotides Encoding Human G-Protein Chemokine Receptor HDGNR10 (now called CCR5)”, which contained a broad claim covering the gene and all medical applications, such as therapies to block or enhance the receptor function. iprcommission.org |
经PCR-SSCP分型筛选后，对该片段的 核苷 酸 序列进行克隆测序和直接PCR测序及比对分析，发现了31个MHC B-G新等位基因；各等位基因主型所含有的亚型数及其在不同品种间的分布极不均衡。 actazool.org | We found 31 novel alleles of B-G genes，and allele distributions at the different breeds were notably non-symmetrical. actazool.org |
所估计的核苷酸转 换数和颠换数随着遗传距离的增加而逐渐增加, 当核苷酸转 换数和颠换数达到平衡后，该片 段 核苷 酸 转换数的增加幅度逐渐高于颠换数。 actazool.org | The number of observed transitions versus tranversions gradually increased with genetic distances, indicating that the nucleotide substitution in the region was not saturated. actazool.org |
过去十年间，相关研究主要集中在作为DNA疫苗或用于基因治疗与传输的DNA、RNA以及短链 寡 核苷 酸 的 使用方面。 malvern.com.cn | In the last decade research has [...] intensified on the use of DNA, RNA, and [...] shorter chain oligonucleotides as DNA vaccines [...]or for gene therapy and delivery. malvern.com |
研究人员发现了一种可使针对杜氏肌营养不良症的反义 寡 核苷 酸 疗 法变得更为有效的辅助药物。 chinese.eurekalert.org | Researchers have discovered a booster drug that could make antisense oligonucleotide therapy more effective for patients with Duchenne muscular dystrophy. chinese.eurekalert.org |
我们对205名对照受试者和229名BPH病人采用直接测序和限制性片段长度多态性分析，在NOS2基因中测出三种 单 核苷 酸 多 态性（SNPs），包括rs2779248（启动子, [...] –278 T/C）、rs10459953（5'-非翻译区）和rs2297518（外显子16，错义，Ser608Leu）。 asiaandro.com | With a cohort of 205 controls and 229 BPH subjects, we genotyped [...] three single nucleotide polymorphisms [...](SNPs) in the NOS2 gene, including rs2779248 [...](promoter, −278 T/C), rs10459953 (5′-untranslated region) and rs2297518 (exon 16, missense, Ser608Leu), using direct sequencing and restriction fragment length polymorphism. asiaandro.com |
培训 班的主要内容包括：国际核苷酸序 列数据库、分子进化与比较基因学、日本 [...] DNA 数据库 （DDBJ）的使用、以及 DDBJ 中的数据库等。 unesdoc.unesco.org | The International Nucleotide Sequence Data [...] Base, molecular evolution and comparative genomics, the use of the DNA Data Bank [...]of Japan (DDBJ) and the databases available in the DDBJ were among the main issues addressed at the course that laid ground for cooperation between Indonesian and Japanese institutions. unesdoc.unesco.org |
所提供的服务包括Sanger及新一代测序、基因分型/SNP分析、基因表达研究 和 核苷 酸 抽 提。 illumina.com.cn | Services provided include Sanger and next-generation sequencing, genotyping/SNP analysis, gene [...] expression studies and nucleic acid extractions. illumina.com |
基因组学方面的进展包括：基因组宽度分析；在理解 单 核苷 酸 (SNP) 多态性 在疾病的作用方面取得进展；在理解复制数量变化在疾病的作用方面取得进展； [...] 功能基因组学；以及加强了对基因调控网络的参与性的理解。 daccess-ods.un.org | Genomics advances have included: genome wide [...] analysis; progress in understanding the [...] role of single nucleotide polymorphisms [...](SNPs) in disease; progress in understanding daccess-ods.un.org |
氨基酸一鈉 (MSG) 幾乎可於所有類別的動 植物食品中找到，而核苷酸則 只能在個別食品中找到，例如IMP主要於牛肉、雞肉、及魚肉等中找到；AMG可於甲殼動 物、軟體動物及差不多所有植物中找到。 ajinomoto.com.hk | IMP is dominant in beef, chicken and fish meat, etc. AMP is found in crustaceans and mollusks as well as in almost all vegetables. ajinomoto.com.hk |
共测定了黄山短尾猴7个群体中的30个样本的mtDNA控制区5′ 端493 [...] bp的序列，只发现了7个变异位点，定义了3种单倍型，单倍型序列之间缺乏变异，种群中 的 核苷 酸 多 样性很低（0.006）；3种单倍型相应地将黄山种群分为了3个亚群，不同亚群之间呈现出一定的片断化分布，从分子水平上初步揭示了短尾猴黄山种群的遗传多样性。 actazool.org | Only 7 variable sites [...] were detected in the nucleotide sequences of 493 bp, [...]all of which were the transitions between T and [...]C. Three haplotypes were identified, and according to the distribution of the haplotypes, we can generally divide the Huangshan population into three subpopulations. actazool.org |
主要产品 有阿昔洛韦（ [...] Acyclovir ）中间体（二乙酰阿昔洛韦、二乙酰鸟嘌呤、阿昔洛韦侧链）、四乙酰核糖、利巴韦林缩合物、次黄嘌呤和乙酰次黄嘌呤、腺嘌呤、胞苷、 6- 氯嘌呤核苷、 6- 氯嘌呤、 6- 氯鸟嘌呤、 N4 - 乙酰胞嘧啶等核苷类及核苷酸类 相关产品；生产技术指标先进，产品质量达到国际、国家级行业标准要求。 beiyangchem.com | Main products include Acyclovir intermediates (Diacetyl acyclovir, Diacetyl guanine, Acyclovir side chain), Tetraacetyl ribose, 2,3,5-Tri-O-triacetyl-beta-D-ribofuranosyl-1,2,4-triazole-3-methyl carboxylate, [...] Hypoxanthine and Acetyl [...] Hypoxanthine, Adenine, Cytidine, 6-Chloropurine nucleoside, 6-Chloropurine, 6-Chloroguanine, 6-Hydroxypurine, N4-Acetyl cytosine, etc. The unique production [...]technology and excellent [...]quality control system guarantee the factory offering top grade products and first class technical service. beiyangchem.com |
本研究通过LA-PCR 技术对草兔线粒体基因组全序列进行PCR 扩增、序列测定和分析,并基于线粒体基因组12 个蛋白质编码基因10 776 bp的核苷酸序列,采用贝叶斯法(BI)和最大似然法(ML)构建哺乳纲(Mammalia) 灵长总目(Euarchontoglires)5 个目12 种动物的系统发育关系,结果支持兔形目(Lagomorpha)的单系起源,其中草兔与欧洲野兔(L. europaeus)亲缘关系最近,两者互为姐妹群,进而与家兔(Oryctolagus cuniculus)构成姐妹群关系。 mammal.cn | Moreover,its subspecies taxonomic status has been under debate for years. In present study,we reporte the complete mitochondrial genomic sequence of the cape hare from Yancheng City,Jiangsu Province,China,and that the gene composition / order of which were identical to that observed in most other mammals. english.mammal.cn |
多数情况下的 [...] RNA聚合酶II和少数情况下的RNA聚合酶III从基因组序列上转录形成前体miRNA（pri-miRNA），这种miRNA可以是几百或几千 个 核苷 酸 的 长度，包含了多个miRNA茎环。 labome.cn | RNA polymerase II, and less often RNA polymerase III transcribe from genomics sequence and produce primary [...] miRNA (pri-miRNA), which could be hundreds or [...] thousands of nucleotides long and contain [...]more than one miRNA stem loops. labome.com |
英汉双解词典包含2273206条英汉词条，基本涵盖了全部常用单词的翻译及用法，是英语学习的有利工具。