| 单词 | 树突状细胞 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 释义 | 树突状细胞 —dendritic cellSee also:树突—dendrite (branched projection of a neuron) 树状细胞—dendritic cell 细胞 n—cytoplasm n 细胞—cell (biology)
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在加盟泽润生物之前，曾博士在世界上开发细胞免疫治疗肿瘤技术的先行者Dendreon公司担任治疗性肿瘤疫苗抗原的生产过程开发部总监，领导细胞培养工艺开发、生物纯化工艺开发，和中试放大技术转移生产支持三个团队，为举世瞩目的利用自 体 树突状细胞 （Dendritic cells）治疗前列腺癌的细胞免疫疫苗Provenge®的抗原研发与商业生产过程提供科学和技术支持。 zerunbio.com | Prior to joining Zerun Biotechnology, Dr. Zeng was the Director of Protein Process Development at Dendreon Corporation (a pioneer in developing active cellular immunotherapeutic vaccines against various cancers), leading three teams (cell culture process development, purification process development, and bioengineering service) [...] to develop novel [...] antigens and also providing scientific and technological support to the antigen manufacturing for Provenge®, the first FDA-approved autologous cellular immunotherapy that uses a patient’s own antigen-presenting cells to stimulate [...]the body’s immune [...]system against prostate cancer. zerunbio.com |
此次，研究小组用老鼠培养出的黑色 素 细胞 ， 查 明了在这 些 树状突 起 形成过程中，被称为“Varp”的Rab21活化因子与其相关。 tohoku.ac.jp | In this study, the research group has revealed that the activation of Rab21 by Varp is required for dendrite formation, by using cultured mouse melanocytes. tohoku.ac.jp |
娇韵诗实验室发现海百合萃取精华能够控 制 s 树突 （ 也 就是阻断黑 素 细胞 向 表 皮分泌出黑色素的“通道”）的延伸。 clarinsusa.com | This is why Clarins Laboratories, who discovered that [...] Sea Lily extract was able to [...] control extension of dendrites - the "arms" of melanocytes which [...]deliver melanin pigments to [...]the epidermis - only use plants from controlled cultivation. clarinsusa.com |
为了能从黑色素细胞到角质细胞中高 效地运输黑色素小体，一直以来都认 为 树状突 起 的 形成很重要，但到此为此的机制并未得到完全清晰的解析。 tohoku.ac.jp | For efficient transfer of melanosomes from melanocytes to keratinocytes, dendrite formation had been considered to be important. tohoku.ac.jp |
国立大学法人东北大学发现了，作为输送黑色素合成酶必须的因子而被熟知的Varp分子有“促进黑色 素 细胞 的 树状突 起 形成”的新作用。 tohoku.ac.jp | Tohoku University has revealed that Varp, known as a molecule essential for transport of melanogenic enzymes, promotes dendrite formation of melanocytes. tohoku.ac.jp |
统的影响”、“毒理机制和方法”(2008 年)；“产后甲醛暴露对老鼠海马状突 起和 大脑半球的锥体细胞数量、细胞层体积的影响：一个体视学研究”(2007 年)；“褪 黑激素可防止甲醛诱导的老鼠前额皮层神经毒害：免疫组织化学和生物化学研 究”(2007 [...] 年)；“咖啡酸苯乙酯对防止老鼠因吸入香烟烟雾造成肝损伤的保护作 [...] 用”(2007 年)；“W-3 必需脂肪酸对防止甲醛诱导老鼠前额皮层神经元损伤的保 护作用”(2007 年)；“W-3 脂肪酸在老鼠脑缺血再灌注模型中的保护作用”(2007 年)。 daccess-ods.un.org | (2008); “Effects of post-natal formaldehyde exposure on pyramidal cell number, volume of cell layer in hippocampus and hemisphere [...] in the rat: a stereological [...]study” (2007); “Melatonin prevents formaldehyde-induced neurotoxicity in prefrontal cortex of rats: an immunohistochemical and biochemical study” (2007); “The protective effects of caffeic acid phenethyl ester (CAPE) against liver damage induced by cigarette smoke inhalation in rats” (2007); “Protective effects of W-3 essential fatty acids against formaldehyde-induced neuronal damage in prefrontal cortex of rats” (2007); “Protective effects of W-3 fatty acids in a rat focal cerebral ischaemia-reperfusion model” (2007). daccess-ods.un.org |
储藏黑色素的；黑色素小体在细胞内移动，从黑色 素 细胞 的 “ 树状突 起 ” 过渡到邻接的形成皮肤或头发的细胞（角质细胞或毛发基质细胞）中，皮肤或头发就变黑了。 tohoku.ac.jp | Mature melanosomes are transported [...] within melanocytes and are [...] eventually transferred from dendrites of melanocytes to neighboring [...]keratinocytes and hair matrix cells. tohoku.ac.jp |
关于镰状细胞贫血 ，我们也制定了防治该疾病的 方案，并在我国卫生部内成立了研究和治疗机构。 daccess-ods.un.org | With regard to sickle-cell anaemia, we also have a programme to fight the disease and a research and treatment facility within our public health ministry. daccess-ods.un.org |
通过将番泻树、橄榄树、悬铃树和豌 豆与猴面 包 树 结 合 ，娇韵诗实验室创造出了独一无二的防晒护理产品——植物性阳光防护元素2（Phyto Sunactyl 2），能够保护皮肤细胞及其 遗传免受太阳的侵袭。 clarinsusa.com | By combining [...] senna, olive, plane tree and pea with baobab, Clarins Laboratories created Phyto-Sunactyl 2, the exclusive complex present in Clarins sun products which protects skin cells and their genetic inheritance against the sun’s aggressions. clarinsusa.com |
除与基因有关的镰状细胞性贫 血症以外，其 它主 要的非传染性疾病如心血管疾病、糖尿病、癌症以及 [...] 慢性呼吸道感染都是由一些常见、可 以改变的风险因 素造成的，即：吸烟、有害使用酒精、不健康的饮食 以及缺乏体育活动。 daccess-ods.un.org | Apart from sickle-cell disease, which [...] is genetically linked, the other major NCDs — cardiovascular diseases, diabetes, cancers [...]and chronic respiratory tract infections — share common and modifiable risk factors, namely tobacco use, harmful use of alcohol, unhealthy diets and physical inactivity. daccess-ods.un.org |
委员会还关切地注意到，镰 状细胞贫血 症是缔约国一个主要的健康问题。 daccess-ods.un.org | The Committee also notes with concern that sickle cell anemia is a major health issue in the State party. daccess-ods.un.org |
2005 年 10 月 11 [...] 日大会第十三次全体会议决定根据总务委员会的报告在其议程中增加项目 5.36 “镰状红细胞症-- 公共卫生的一项优先工作”和 [...] 14.3“加强与几内亚比绍共和国的合作”。 unesdoc.unesco.org | At its 13th plenary meeting, on 11 October 2005, the General Conference decided to add to its agenda, [...] pursuant to the report of its General [...] Committee, items 5.36 “Sickle-cell anaemia, a public [...]health priority” and 14.3 “Strengthening [...]of cooperation with the Republic of Guinea-Bissau”. unesdoc.unesco.org |
由于Varp与皮肤或毛发变暗的重要两个过程（黑色素合成酶的输送 和 树状突 起 的 形成）相关，因此，如果在对Varp的机能有阻碍作用或使之安定的药剂的筛选取得进展，那么今后我们可以期待其与皮肤美白的维持及白发的预防相关联的可能性。 tohoku.ac.jp | Since Varp is related to the two important processes for darkening skin and hairs, that is, transport of melanogenic enzymes and dendrite formation, [...] screening of medical [...]agents inhibiting or stabilizing Varp functions will lead to keep our skin white and prevent our hairs from becoming gray. tohoku.ac.jp |
米哚妥林是一种针对FLT3络氨酸激活酶的定向小分子抑制剂，目前正处于第三阶段临床开发中，给新确诊的 F L T 3 突 变 急性 髓 细胞 白 血病患者服用米哚妥林或服用安慰剂并结合化学疗法（NCT00651261）进行对比试验。 tipschina.gov.cn | Midostaurin, a targeted small molecule inhibitor of FLT3 tyrosine kinase, is currently in Phase III [...] clinical development for newly [...] diagnosed patients with FLT3 mutated AML who are receiving [...]midostaurin or a placebo in combination [...]with chemotherapy (NCT00651261). tipschina.gov.cn |
应当重视提高该地区各国在以下方面 的能力：确保可持续安全饮用水的供应，城市水资源的开发和管理战略，以及与城市及其周 边排水和卫生相关的问题，恢复恶化了的水生态系统，对正在消失的水资源进行研究、预防 和解决与水资源问题有关的冲突问题 ，建立分地区水观察站、研究某些生态系统、尤其 红树 林系统的可持续性，以及利用当地知识来保护环境。 unesdoc.unesco.org | Emphasis should be placed on enhancing the capabilities of countries of the region to secure sustainable and safe drinking water supplies, urban water development and management strategies as well as issues related to urban and peri-urban drainage and sanitation, the rehabilitation of degraded water ecosystems, research on [...] disappearing water [...] resources, aspects of conflict prevention and resolution in relation to water issues, the creation of subregional water observatories, research in the sustainability of certain ecosystems and in particular of mangrove systems, [...]as well as drawing on [...]local knowledge for the protection of the environment. unesdoc.unesco.org |
在我国 人口中肆虐的主要非传染性疾病有：心血管病、 糖尿病、癌症、慢性呼吸道疾病、血红蛋白病， 尤其是镰状细胞疾病 、心理健康疾病、道路交通 伤害、暴力，各国的发病率各不相同。 daccess-ods.un.org | The major NCDs ravaging our populations include cardiovascular diseases, diabetes mellitus, cancers, chronic respiratory diseases, hemoglobulinopathies, especially sickle cell disease, mental health disorders, road traffic injuries, violence, with morbidity varying from country to country. daccess-ods.un.org |
即，首次明确了Varp是使Rab21活化，并参与 对 树状突 起 形 成所必须的膜或蛋白质突起端进行供给。 tohoku.ac.jp | Thus, it is elucidated that the Rab21 activation by Varp is involved in supplying new membranes and/or proteins to the tips of dendrites for dendrite outgrowth. tohoku.ac.jp |
请总干事就本决议的实施情况，包括国家、地区和国际各级在防治 镰 状 红 细胞 症 方面所 作的努力及其在全世界产生的影响向大会第三十四届会议提交报告。 unesdoc.unesco.org | Invites the Director-General to submit to it at its 34th session a report on the implementation of this resolution, including the efforts made at the national, regional and international levels to combat sickle-cell anaemia and its consequences worldwide. unesdoc.unesco.org |
会议建议，文件 31 C/4 [...] 介绍教科文组织战略所使用的方法（ 树状 结 构 ，即在本组织统一专 题项下有一些目标和优先事项）应作为改进 [...]32 C/5 草案的基础。 unesdoc.unesco.org | It is suggested that the device used to [...] represent UNESCO’s strategy in document 31 C/4 [...] (the structural tree, which groups [...]objectives and priorities under a unifying theme [...]for the Organization) should be used as the basis for improvements in the draft document 32 C/5. unesdoc.unesco.org |
但是，本周发表在《科学快讯》中的2项新的研究证明，大约71%的人类黑色素瘤在TERT基因中具有2种 体 细胞突 变 中 的1种，该基因编码端粒酶的1个亚基；端粒酶是覆盖在染色体端部的酶。 chinese.eurekalert.org | Two new studies in this week’s issue of Science Express, however, demonstrate that [...] about 71 percent of human melanomas harbor [...] one of two somatic mutations in the TERT gene, [...]which encodes a subunit of telomerase, [...]the enzyme that caps the ends of chromosomes. chinese.eurekalert.org |
食道癌有两种类型：鳞状细胞癌和 腺癌。 tipschina.gov.cn | There are two types of EC: squamous cell carcinoma and adenocarcinoma. tipschina.gov.cn |
我国的非传染性疾病包括心血管疾病、癌症、动脉高 血压、糖尿病、镰状细胞贫血 、精神疾病、布路里溃 疡和坏疽性口炎等，这仅仅是几个例子而已。 daccess-ods.un.org | NCDs in my country include cardiovascular diseases, cancers, arterial hypertension, diabetes, sickle cell anaemia, mental illness, Buruli ulcers and noma, to name but a few. daccess-ods.un.org |
最后，重大计划 V 树立了 一个可喜的榜样，它拿出了正常预算资金的至少 20%用于跨 部门活动，并且特别侧重于艾滋病毒和艾滋病、气候变化(包括可持续发展教育和科学教 育)、新知识的获取方法(包括信息与传播技术的强化学习、媒体和信息扫盲)、多样性和相互 了解(包括使用多种语言和遗产保存)，以及对于 冲 突 后 国 家和受灾国家的支持。 unesdoc.unesco.org | Finally, Major Programme V has set a welcome example by earmarking at least 20% of [...] its regular budget resources [...] for intersectoral engagement, with particular focus on HIV and AIDS; climate change (including education for sustainable development and science education); new knowledge acquisition processes (including ICT-enhanced learning; media and information literacy); diversity and mutual understanding (including multilingualism and heritage preservation); and support to countries in post-conflict and post-disaster situations. unesdoc.unesco.org |
通过了解镰状细胞性贫 血、所用药物和生 活方式的相关知识，您可以减轻甚至不会 出现疼痛发作和其他并发症。 amerihealthmercyhp.com | By learning about sickle cell anemia, your medicines and lifestyle, you can decrease or even not have pain episodes and other complications. amerihealthmercyhp.com |
近年来，因特网和社交联网工具日益流行，如果加以有效使用可以帮 助树立本组织在状况中 、可接触和可及的形象。但与此同时，咨询委员会指出， 更传统的宣传手段(例如广播和印刷媒体)依然是确保有效宣传本组织信息，特别 是在发展中国家有效宣传本组织信息工作的重要组成部分。 daccess-ods.un.org | At the same time, however, the Committee notes that more traditional means of communication (i.e. radio and print media) remain an important part of efforts to ensure that the message of the Organization is effectively promoted, particularly in developing countries. daccess-ods.un.org |
我们乐观地注意到最近的科研突破， 即在 CD4 细胞数量 较高的情况下启动抗逆转录病毒治疗，可使 艾滋病毒感染者提高生活质量和延长寿命，并可作为 预防措施，打破病毒从感染者传播至非感染者的循 环。 daccess-ods.un.org | We note with [...] optimism recent breakthroughs in research, whereby the initiation of antiretroviral therapy when the CD4 count is high provides [...]people living with [...]HIV better quality of life and longevity and acts as a preventive measure to break the cycle of the transmission of the virus from the infected to the uninfected. daccess-ods.un.org |
乔木给60米高； 树干直径达2米；树皮淡褐色，突然开始不规则的盘子； 树冠圆锥状； 幼 时的小枝下垂，淡褐色或者淡色的灰色，无毛； 很少，冬芽红棕色，圆锥状或卵球形，开阔的的鳞片稍小枝在基部。 flora.ac.cn | Trees to 60 m tall; trunk to 2 m d.b.h.; bark pale brown, breaking into irregular [...] plates; crown conical; branchlets pendulous, [...]pale brown or pale gray when young, glabrous; winter buds reddish brown, conical or ovoid, scales slightly open, rarely appressed at base of branchlets. flora.ac.cn |
Genection为医师提供了一个全球性的专业网络平台，供他们使用全部临床可控的基因测试菜单，包括常规和深度基因测试、外显子组和全基因组测序、癌症 体 细胞突 变 检 测以及药物基因组学等。 tipschina.gov.cn | Genection provides physicians with a dedicated online platform for global access to the entire clinically-actionable genetic test menu, including both [...] routine and esoteric genetic tests, exome and whole genome [...] sequencing, cancer somatic mutation testing, and [...]pharmacogenomics. tipschina.gov.cn |
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