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单词 多态性
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约500 000个DNA功能模块的变种(单核苷 多态性 , SN P,它们遍布DNA的整个长度,并被证明与某些生理和行为特征或疾病敏感性相关)正在接受常规分析。
project-syndicate.org
Already, variations in the composition
[...]
of about 500,000 DNA building
[...] blocks (SNPs or Single Nucleotide Polymorphisms), spread [...]
over the total length of the DNA
[...]
and shown to correlate with particular physical and behavioral characteristics or susceptibility to diseases, are being analyzed routinely.
project-syndicate.org
关于XRCC1 Arg399Gln多态性是不 是神经胶质瘤的危险因素,结论尚不统一。
chinese.eurekalert.org
Whether XRCC1
[...] Arg399Gln polymorphism is a risk factor for glioma remains controversial.
chinese.eurekalert.org
因此,在 1999
[...] 年十家大型制药公司和英国的维康基金会 (Wellcome Trust) 一起成立了一个协会64 ,发现 并绘制三十万个单核苷多态性 (SNP) 的图形65 。
iprcommission.org
Thus, in 1999, ten large pharmaceutical companies and the U.K. Wellcome Trust established a consortium64 to find and map 300,000 common SNPs.65 This has generated a widely accepted, high-quality, extensive, publicly available map using SNPs as
[...]
markers evenly distributed throughout
[...] the human genome, many of which will be used to locate targets for [...]
drug research.
iprcommission.org
通过随机扩多态性DNA(R APD) 方法,我们对河北省固安县牛驼镇王龙村附近的大仓鼠(Cricetulus [...]
triton)种群的遗传多样性进行了研究。
actazool.org
The genetic diversity of rat-like hamster(Cricetulus [...]
triton) populations in Hebei Province,China was investigated using
[...]
the randomly amplified polymorphic DNA(RAPD) method through the polymerase chain reaction(PCR).
actazool.org
位于尿激酶型纤溶酶原激活剂基因第6外显子rs2227564位点的C/T错 多态性 被 认为是可能与阿尔茨海默病发病相关的热议位点。
chinese.eurekalert.org
A missense C/T polymorphism in exon 6 (the NCBI rsID is rs2227564) of the urokinase-type plasminogen activator gene has been identified as a possible hot spot for Alzheimer’s disease risk.
chinese.eurekalert.org
结果表明:在正常人细胞DNA中存在鹌鹑Quox-1基因的同源序列,在LCE等肿瘤细胞中Quox-1基因表现出明显的限制性酶切片 多态性 和 基 因扩增现象。
actazool.org
There was homologous sequence of Quox-1 in normal human leukocyte, and some tumor
[...]
cells (LCE and  HeLa cells), it appears Restriction
[...] Fragment Length Polymorphism (RFLP) and may  [...]
undergo gene amplification.
actazool.org
再者,现代的法医学和遗传药理学亦以D NA 的 多态性 为 根 基。
shawprize.org
Moreover, the modern fields of forensic medicine and
[...] pharmacogenetics are based on DNA polymorphism.
shawprize.org
子代的平均期望杂合度(He)、平均观测杂合度(Ho)和平 多态性 信 息 含量(PIC)等指标均低于亲代。
actazool.org
The average heterozygosity of
[...] offspring and polymorphic information content(PIC)etc were lower than those of their [...]
parents.
actazool.org
脱氧核糖核酸(DNA)的多态性的发 现为整个人类遗传学带来真正革命性的改变,分子遗传学亦因此而诞生。
shawprize.org
The discovery of DNA polymorphism has truly revolutionized [...]
the entire field of human genetics and was directly responsible
[...]
for the birth of molecular genetics.
shawprize.org
此外,在总体分析及所有亚组分析中,我们均未见43 26 C / G 多态性 与 PC a侵袭性有任何显著联系。
asiaandro.com
The overall analyses and all subgroup analyses showed no significant association between
[...] the 4326C/G polymorphism and PCa aggressiveness.
asiaandro.com
在此之前,在人与猿之间只确认了2种共有 多态性 : 主要组织相容性复合体或MHC的变体,及作为不同血型基础的ABO血型系统中 多态性。
chinese.eurekalert.org
Until now, only
[...] two shared polymorphisms between humans and apes had been identified: variants in the major histocompatibility complex, or MHC, and polymorphisms at the ABO blood group system, which underlies various blood types.
chinese.eurekalert.org
基因组学方面的进展包括:基因组宽度分析;在理解单核苷酸( SN P) 多态性 在疾病的作用方面取得进展;在理解复制数量变化在疾病的作用方面取得进展; 功能基因组学;以及加强了对基因调控网络的参与性的理解。
daccess-ods.un.org
Genomics advances have included: genome wide analysis; progress in understanding the role of single nucleotide polymorphisms (SNPs) in disease; progress in understanding
daccess-ods.un.org
应用聚合酶链式反应-限制性片段长 多态性 分 析 (PCR-RFLP)和芯片生物分析系统建立了台湾海峡常见石斑鱼和鲷鱼的分子生物学品种鉴定新方法。
chrom-china.com
Polymerase chain reaction-restriction
[...] fragment length polymorphism (PCR-RFLP) analysis [...]
and lab-on-a-chip system were used
[...]
to identify grouper and snapper species in Taiwan Strait.
chrom-china.com
一项新的对人类及黑猩猩进行的全基因组分析披露,这两个物种在数百万年中同时拥有着某些相同的会导 多态性 —— 即在同一物种中有着不同的物理形式——的突变组合。
chinese.eurekalert.org
A new genome-wide analysis of both humans and chimpanzees reveals that the two species have shared
[...]
some of the same combinations of mutations
[...] that result in polymorphisms, or different [...]
physical forms within the same species, for millions of years.
chinese.eurekalert.org
从研究DNA的多态性所得 到的知识,对今天了解基因组的结构及功能有关键的作用。
shawprize.org
Moreover, the knowledge
[...] gained on DNA polymorphism was a principal [...]
contributing factor to our current understanding of the
[...]
structure and function of the human genome.
shawprize.org
40只朱鹮在前白蛋白(Pre)、白蛋白(Alb)、后白蛋白(Pa)、运铁蛋白(Tf)共4个蛋白质位点上没有发 多态性。
actazool.org
The results showed no polymorphism  in 4 blood protein [...]
loci including Pre, Alb, Pa and Tf loci in 40 birds.
actazool.org
他们着重于建设全基因组的转录网络模型并综合运用了基因表达微阵列,大规模的蛋白质-蛋白质和蛋白质-DNA相互作用分析,系统性的RNAi分析和高通量基 多态性 检 测 等方法。
tilsi.org
They have particular focus on building genome-wide models of transcriptional networks, and they use an integrated approach that makes use of gene expression microarrays, large-scale
[...]
protein-protein and protein-DNA interaction analyses,
[...] systematic RNAi analysis and high throughput polymorphism detection.
tilsi.org
用Southern杂交法研究Quox-1基因在人正常白细胞、LCE细胞及其HeLa细胞中的限制性酶切片 多态性 ; 免 疫组织化学方法研究Quox-1基因在人细胞中的表达。
actazool.org
In order to study the relationship between the Quox-1 and the tumorigenesis and cell maligimization,  cellular genomic DNA of normal human leukocytes and some tumor cells (LCE and HeLa cells) were extracted using proteinase K method and were restricted with EcoRⅠ.
actazool.org
我们对205名对照受试者和229名BPH病人采用直接测序和限制性片段长 多态性 分 析 ,在NOS2基因中测出三种单核苷 多态性 ( SNPs),包括rs2779248(启动子, –278 T/C)、rs10459953(5'-非翻译区)和rs2297518(外显子16,错义,Ser608Leu)。
asiaandro.com
With a cohort of 205 controls and 229 BPH
[...]
subjects, we genotyped
[...] three single nucleotide polymorphisms (SNPs) in the NOS2 gene, including rs2779248 (promoter, −278 T/C), rs10459953 (5′-untranslated region) and rs2297518 (exon 16, missense, Ser608Leu), using direct sequencing and restriction fragment length polymorphism.
asiaandro.com
结果表明:雀形目鸟类基因组大小存在遗 多态性 , 不 同类群在酶切类型上表现出各自的特点,雀形目鸟类与非雀形目鸟类在线粒体DNA的进化速率有着相同的特点,化石记录的地质年代与线粒体DNA分子时钟记录的年代有着惊人的吻合,这两个互为独立事件的统一,提示线粒体DNA作为分子进化的良好工具。
actazool.org
Using this
[...] evolutionary rate, our results indicate that these taxa diverged 4 million years ago, which [...]
is identical to what
[...]
is suggested by the fossil record. This suggests that mitochondrial DNA may provide an appropriate molecular clock for research on the evolutionary history of birds.
actazool.org
对于许多太平
[...] 洋小岛屿发展中国家而言,要走上绿色经济之路,就要实现绿色增长,而这 将可确保能保护具有全球重要性的宝贵的 态多 样 性。
daccess-ods.un.org
For many of the Pacific small island developing States, the path to a green
[...]
economy required achieving green growth, which would ensure the preservation of
[...] valuable biodiversity of global significance.
daccess-ods.un.org
城市历史景观方法旨在维持人类环境的质量,在承认其 态性 质 的同时提高城市空间的生 产效用和可持续利用,以及促进社会和功能方面 多 样 性。
unesdoc.unesco.org
The historic urban landscape approach is aimed at preserving the quality of the
[...]
human environment,
[...] enhancing the productive and sustainable use of urban spaces, while recognizing their dynamic character, and promoting social and functional diversity.
unesdoc.unesco.org
2010 年的态多样性目标后来被纳入千年发 展目标。
daccess-ods.un.org
The 2010 biodiversity target was subsequently [...]
integrated into the Millennium Development Goals.
daccess-ods.un.org
全球性和多学科的努力,例如千年生态系统评估、国际农业知识评估, 以及科学和技术促进发展,已经评估地球上的 态多 样 性 和 农业生态区以及其他 环境事务的健全程度。
daccess-ods.un.org
Global and multidisciplinary efforts, such as the Millennium Ecosystem Assessment and the International Assessment of Agricultural Knowledge, Science and Technology for
[...]
Development, have assessed the health of
[...] the Earth’s biodiversity and agroecological zones, and other [...]
environmental services.
daccess-ods.un.org
经社会了解到太平洋小岛屿国家为保护生 多 样 性 和 维系 生 态 系 统 服 务能力而出台的各种举措,诸如太平洋最大的海洋保护区——基里巴斯的菲 [...]
尼克斯群岛保护区、以及涵盖亚太区域若干国家的珊瑚礁三角区倡议——这 一地区拥有世界最大面积的红树林,提供了金枪鱼和其他全球重要鱼种产卵
[...]
和幼体生长的重要区域。
daccess-ods.un.org
The Commission was informed of initiatives that were being undertaken by Pacific
[...]
island developing countries to protect
[...] biodiversity and the maintenance of ecosystem services, such [...]
as the Phoenix Islands Protected
[...]
Area in Kiribati, the largest marine protected area in the Pacific Ocean, and the Coral Triangle Initiative, which covered a number of countries in the Asia-Pacific region, included the greatest extent of mangrove forests in the world and provided a critical spawning and juvenile growth area for tuna and other globally significant fish species.
daccess-ods.un.org
它强调阿富汗对普遍定期审议进程采取了建 性态 度, 表示民主的巩固不应因塔利班的破坏活动 多 年 战 争对平民的损害而受到阻碍。
daccess-ods.un.org
It highlighted Afghanistan’s
[...] constructive approach to the universal periodic review process, and stated that the consolidation of democracy should not be hindered by destructive Taliban activities or damage to the civilian population from many years of war.
daccess-ods.un.org
加 拿 大艾滋病毒/艾滋病法律网
[...] 代表加拿大艾滋病毒/艾滋病法律网 和国 际 男 女 同 性 恋 人权委员会表示 , 赞 赏 巴多 斯代表团 所采取的建性态 度和对各 项建议所作的考虑。
daccess-ods.un.org
On behalf of the Canadian HIV/AIDS Legal Network and the International Gay and Lesbian Human Rights Commission, the Canadian
[...]
HIV/AIDS Legal Network
[...] expressed appreciation for the constructive approach of the delegation and [...]
the consideration given to all recommendations.
daccess-ods.un.org
本报告所述期 间印发的出版物包括:2006
[...] 年关于富钴结壳和海山动物群分布 态多 样 性 的 研 讨 会会议记录,2003 年关于建立赤道以北太平洋克拉里昂-克利珀顿断裂带多金属 [...]
结核资源地质模形的研讨会会议记录,以及国际海底管理局《技术研究》第 4
[...]
号: “有关《联合国海洋法公约》第八十二条执行情况的问题”。
daccess-ods.un.org
Publications issued during the period covered by the present report include the proceedings of the March
[...]
2006 international Workshop on Cobalt-rich
[...] Crusts and the Diversity of Distribution [...]
Patterns of Seamount Fauna, the proceedings
[...]
of the May 2003 Workshop on the Establishment of a Geological Model of Polymetallic Nodule Resources in the Clarion-Clipperton Fracture Zone (CCZ) of the Equatorial North Pacific Ocean, and ISA Technical Study No. 4, entitled “Issues associated with the implementation of article 82 of the United Nations Convention on the Law of the Sea”.
daccess-ods.un.org
人与生
[...] 物圈计划(MAB)与“善待自然国际”合作,共同举办了“隔离生物炭和保护环境,抵御气候变化: 促进农村发展、能源解决方案和 态多 样 性 ” 国际论坛(2006 年 3 月)。
unesdoc.unesco.org
MAB teamed with Pro-Natura International to present a forum on Bio-Carbon
[...]
Sequestration and Conservation to Combat Climate Change: Promoting Rural Development, Energy
[...] Solution and Biodiversity (March 2006).
unesdoc.unesco.org
公司拥有全套不锈钢生物液体发酵设备和精密的检测仪器,技术力量雄厚,结合发酵经验进行技术优化和改良生产工艺,经液体深层发酵或 态多 次 发 酵培养、过滤、干燥、粉碎制成的各种药用真菌菌丝粉,严格按制药标准组织生产,并不断优化产品结构,提高品质,有系统的质量保证体系,年产生物发酵产品300吨,产品广泛用于药品及保健食品的开发生产和植物提取上,产 性 状 稳 定,主要质量指标高于其它同类产品。
dbslz.com
The company has a full set of stainless steel and  biological fluid fermentation equipment and sophisticated testing instruments, strong technical force, combined with fermentation experience to optimize the technology
[...]
and improve production craft, the various medicinal powder which is cultivated, separated filtration、drying、crushed through the
[...] submerged liquid fermentation or two-state fermentation for many times, are strictly according to pharmaceutical standards to organize production, and optimize the product structure, improve the quality, and also it has systematic quality assurance system, the annual output of fermentation products are 300 tons, the products are widely used in development and production of medicine and healthcare foods, and also in plant extract field, the character of product is stable, the main quality indicators are than other similar products.
dbslz.com
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