| 单词 | 基因组 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 释义 | 基因组 noun, plural —genomics plExamples:人类基因组计划—Human Genome Project See also:基因 n—genome n • genomic n • gene n • genetics pl
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生物技术的发展已 使一些基础科学领域诸如基因组学等被认为具有潜在的巨大商业价值。 iprcommission.org | The development of biotechnology has resulted in some [...] areas of basic science, such as genomics, being perceived [...]as having potentially large commercial value. iprcommission.org |
或许结合不同方式的最好的例子是对脑炎支原体的分 析，其中结合了基因组学、 代谢学、蛋白质组学、结构信息以及分子信息。 daccess-ods.un.org | Perhaps the best example of combining different approaches was the characterization [...] of Mycoplasma pneumoniae which included [...] the integration of genomic, metabolic, [...]proteomic, structural and cellular information. daccess-ods.un.org |
除了控制细菌细胞的基因组的化 学合成( 克莱格·温特尔人工生命) ，其他方 法包括：通过在酵母中制作新陈代谢途径生产抗疟疾药物的前体；合成哺乳动物 基因电路揭示抗结核化合物；广泛存在的生物计算的展示；以及制作大肠杆菌以 [...] 探测和杀死人体内病原体。 daccess-ods.un.org | In addition to the chemical [...] synthesis of a genome able to control a bacterial cell (Craig Venter’s artificial [...]life) other important [...]stepping stones include: the engineering of the metabolic pathway in yeast to produce the precursor of an anti-malarial drug; the creation of a synthetic mammalian gene circuit that revealed anti-tuberculosis compounds; a demonstration of distributed biological computation; and the engineering of an E. coli to sense and kill a human pathogen. daccess-ods.un.org |
交流关于人体基因组项目等开放式合 作项目以及关于知识产权模式方面的 经验。 wipo.int | To exchange experiences on open collaborative projects such as [...] the Human Genome Project as well as on intellectual [...]property models. wipo.int |
自然界中的，天然生物过程中的，以及生物材料中的任何生物，不管是一个完整的生物还 [...] 是某个生物的一部分，无论是存在于自然界中的，还是能够分离的，包括任何生物 的 基因组 和种质。 iprcommission.org | Any living thing, either complete or partial, as found in nature, natural biological processes, and [...] biological material, as existing in nature, or able to be separated, [...] including the genome or germ plasm [...]of any living thing. iprcommission.org |
作为一个研 [...] 究和开发中心，新加坡正在借助私营部门的努力，并 支持农业企业尝试将基因组学应 用于农业。 daccess-ods.un.org | As a research and development hub, [...] Singapore was leveraging private-sector efforts and supporting agribusinesses [...] attempting to apply genomics to agriculture. daccess-ods.un.org |
已 围绕下列假设做过研究：(a) 细胞和组织对低剂量辐射的适应性可使它们对癌症 的发展更具抵抗力（适应性反应）；(b) 辐射对免疫系统的影响——免疫系统负责 [...] 识别并摧毁异常细胞——可影响癌症发展的可能性；以及(c) 辐射可产生变化， 从而对细胞 DNA [...] 的稳定产生持久的、可传递的影响（ 基因组 不 稳 定性），并且（或 者）激发从受损细胞向未受损的邻界细胞传送信号（旁观者效应）；基因不稳定 [...] 和旁观者效应被认为是改变辐射相关癌症风险的可能因素。 daccess-ods.un.org | There have been studies relating to the following hypotheses: (a) that adaptation of cells and tissues to low doses of radiation might cause them to become more resistant to cancer development (adaptive response); (b) that the effects of radiation on the immune systems, which recognize and destroy abnormal cells, could influence the likelihood of cancer development; and (c) that radiation can produce changes that create long-lasting and [...] transmissible effects on the stability of [...] cellular DNA (genomic instability) and/or [...]trigger the transfer of signals from [...]damaged cells to their undamaged neighbours (bystander effects); both genomic instability and bystander effects have been suggested as possible factors that modify radiation-associated cancer risk. daccess-ods.un.org |
在规范领域，已加强行动（i）使各会员国了解处理科技进步产生的伦理挑战的迫切需要， 主要是通过宣传生物伦理学领域的三大宣言：世界人 类 基因组 与 人 权宣言、国际人类基因数据宣 言和世界生物伦理与人权宣言；（ii）鼓励各会员国批准新通过的《反对在体育运动中使用兴奋 剂国际公约》（2005 年）。 unesdoc.unesco.org | In the normative field, action was strengthened (i) to sensitize Member States about the urgent need to address ethical challenges arising from the advances made in science and technology, notably through the dissemination of the three declarations in the field of bioethics he Universal Declaration on the Human Genome and Human Rights; the International Declaration on Human Genetic Data; and, the Universal Declaration on Bioethics and Human Rights) and (ii) to encourage Member States to ratify the newly adopted International Convention against Doping in Sport (2005). unesdoc.unesco.org |
在化学和生物科学方面，教科文组织推动建立了国际膜科学与技术中心（澳大利亚肯辛 顿）、国际细胞和分子生物学中心（ICCMB，波兰华沙）和一些生物技术教育和培训中心 [...] （BETCEN），如设在中国、匈牙利、墨西哥、巴勒斯坦权力机构和南非的中心，以及最近 [...] 在印度新德里成立的教科文组织第二类生物技术培训和教育地区中心和在以色列雷霍沃特成 立的教科文组织第二类国际生物信息学 、 基因组 学 和 蛋白质组学培训中心（国际生物组学中 心）。 unesdoc.unesco.org | In the chemical and biological sciences, UNESCO promoted the establishment of the International Centre for Membrane Science and Technology (Kensington, Australia), the International Centre for Cell and Molecular Biology (ICCMB, Warsaw, Poland), and a number of the Biotechnology Education and Training Centres (BETCENs) such as those situated in China, Hungary, Mexico, the Palestinian Authority, and South Africa, as well as the recently established UNESCO category 2 Regional Centre for Biotechnology Training and Education in New Delhi, India, and the UNESCO [...] category 2 International [...] Bioinformatics, Genomics and Proteomics Training Centre in Rehovot, Israel [...](International BIOmics Centre). unesdoc.unesco.org |
遗传物质包括染色体、基因组、质 粒、转位子和载体(包括转基因的、非转 基因的、以及整体或部分化学合成的)。 daccess-ods.un.org | Genetic elements include inter alia chromosomes, genomes, plasmids, transposons, and vectors whether genetically modified or unmodified, or chemically synthesized in whole or in part. daccess-ods.un.org |
东北大学大学院医学系研究科放射性同位素中心的本桥Hozumi准教授，与同医化学领域的光石阳一郎博士、田口惠子助教、山本雅之教授、东京大学先端科学技术研究中心的油谷浩幸教授、国立癌研究中心研究所 癌 基因组 学 研 究领域的柴田龙弘领域长的研究小组，共同研究发现了导致癌细胞恶化的代谢控制组织。 tohoku.ac.jp | Associate Professor Hozumi Motohashi at Center for Radioisotope Sciences, Tohoku University Graduate School of Medicine, Dr. Yoichiro Mitsuishi, Assistant Professor Keiko Taguchi, and Professor Masayuki Yamamoto at Division of Medical Biochemistry, Tohoku University [...] Graduate School of [...] Medicine, Professor Hiroyuki Aburatani at Research Center for Advanced Science and Technology, University of Tokyo, and Division Leader Tatsuhiro Shibata at the National Cancer Center have jointly [...]discovered the metabolic [...]control mechanism that drives the malignant evolution of cancer cells. tohoku.ac.jp |
这不仅反映出科 学家和负有不同任务的组织之间进行跨学科协作是一大挑战，而且直接表明有 [...] 必要明确地将空间技术纳入公认的公共卫生监督职能中，并与其他快速发展的 医疗诊断技术（即基因组学、 纳米技术）、分析技术（即地理信息系统和建模） [...]和信息技术（即基于互联网的数据获取和警报系统）协同发挥作用。 daccess-ods.un.org | This reflects not only the sizeable challenge of transdisciplinary collaboration among scientists and organizations with different mandates, but also speaks directly to the need to explicitly integrate space technologies into recognized public health surveillance functions and in synergy with [...] other fast-developing medical diagnostic [...] technologies (i.e. genomics, nanotechnology), [...]analytical technologies (i.e. geographic [...]information systems and modelling) and information technologies (i.e. Internetbased data capture and alert systems). daccess-ods.un.org |
ChIP和ChIP-on-chip 实验可以提供某个启动子上组蛋白修饰的信息，修饰状态变化的动力学，以及在某个基因或调控序列中，或在整 个 基因组 中 组 蛋白修饰所在的位置。 labome.cn | ChIP and ChIP-on-chip experiments can provide information about histone modification at a promoter of interest, the kinetics of change [...] in the modification [...] status, as well as the location of histone modifications with respect to a gene or regulatory sequence, or throughout the genome. labome.com |
Jim Kaput解释了为什么应对营养不良的举措应该考虑营 养 基因组 学 — —食品与遗传结构之间的相互作用。 scidev.net | Jim Kaput explains why efforts to tackle malnutrition should consider nutrigenomics — the interplay between food and genetic make-up. scidev.net |
医学成像、基因组、结 构生物学、综合生物系统、生物信息学和健康信息学为生命科学研究人员提供了强大且多用途工具，来研究分子、复杂生物系统( [...] 从蛋白质、细胞、组织器官到有机体)、疾病性质等等。 australiachina.com.au | Medical imaging, genomics, structural biology, [...] integrated biological systems, bioinformatics and health informatics are [...]providing powerful and versatile tools for life sciences researchers to investigate the structure and interaction of molecules, complex biological systems (from proteins, cells, tissues, organs, up to organisms), the nature of disease and more. australiachina.com.au |
因此, 本研究使用了一个 新颖的比较基因组学的方法, 命名为全长驱动蛋白 预测方法(FKPP), [...] 通过片段的驱动蛋白序列的进化 保守性来预测全长的序列. biocuckoo.org | Thus we employ a [...] novel comparative genomics approach, named [...]full-length kinesin prediction program (FKPP), to predict the [...]full-length sequence of fragment kinesins based on their evolutionary conservation. biocuckoo.org |
该方法主要特点在于对标本进行预处理，在保证不使DNA进一步降解的前提下，首先去除标本中所含的福尔马林溶液的成分，然后利用改进的酚氯仿抽提法提取该类标本 的 基因组 D N A ，再进一步用透析法纯化DNA。 actazool.org | First, remove the formalin from the specimen under the [...] condition that the genomic DNA is not further [...]degraded. actazool.org |
本文提出了一种从浸泡在福尔马林的大仓鼠肝脏和日本鳗鲡肌肉标本中提 取 基因组 D N A 的 新方法。 actazool.org | This paper reports a new method to extract genomic DNA from the liver specimen of rat like hamster (Cricetulus triton) and muscle specimen of Japanese eel (Anguilla japonica) preserved in formalin. actazool.org |
如果全长的拼接序列不能很好地定位 在 基因组 上(如存在不能匹配的片段 填补空白的部分片段序 列不能定位在基因组上 原始的基因结构不完整 BLAT 的比对结果分数下降超过 10%), 则将拼接出 来的序列视为不合格样品而舍弃. biocuckoo.org | If the full length “chimeric” sequence cannot be localized on genome properly, or the complemented stretches cannot be localized on genome, or original gene structure is heavily disrupted, or BLAT alignment SCORE decrease significantly (>10%), we consider that our chimeric sequence to be improper and reject it. biocuckoo.org |
通常，我们需要鉴别或确认将要植入寄 主 基因组 的 编码序列和非编码 序列的特征。 excellencethrou...stewardship.org | It is usual practice to identify or confirm the identity of the coding and non-coding sequences that [...] will be inserted into the host genome. excellencethrou...stewardship.org |
作物、牲畜、鱼类和树木的新培育技术和改良品种可以通过加快工艺流程 进行开发，诸如传统参与性育种与分子标记辅助选择 、 基因组 学 和 转 基 因 方 法相 结合。 daccess-ods.un.org | New cultivation techniques and improved varieties of crops, livestock, fish, and trees can be developed through accelerated processes, [...] such as traditional and participatory breeding combined with [...] marker-assisted selection, genomics and transgenic approaches. daccess-ods.un.org |
相比于基因组包含的全部基因，人类蛋白质组包含了更多的功能性多肽，部分归因于，翻译的同时和翻译后的蛋白修饰（图1A）。 labome.cn | Human proteome consists of significantly more functional polypeptides than the collection of genes in the genome, [...] due, in part, to [...]co- and post-translational protein modifications (Fig 1A). labome.com |
在社会科学和人文科学科制定生物伦理领域标准的行动中，教科文组织通过 了三项宣言——《世界人类基因组与 人 权宣言》(1997 年)、《世界人类遗传数据 宣言》(2003 年)和《世界生物伦理与人权宣言》(2005 年)，其中广泛涉及不歧 视问题。 daccess-ods.un.org | Within its standard-setting action in the field of bioethics carried out by the Social and Human Sciences Sector, UNESCO has adopted three Declarations — the Universal Declaration on the Human Genome and Human Rights (1997), the International Declaration on Human Genetic Data (2003) and the Universal Declaration on Bioethics and Human Rights (2005) — in which the issue of non-discrimination is extensively addressed. daccess-ods.un.org |
1991年，国家卫生研究所一位杰出的科学家克雷格.温特博士建议与其测序人体所 有 基因组 ， 不 如蛋白质合成的基因会更容易，因为基因只占DNA的2%。 youlinmagazine.com | In 1991, a brilliant NIH scientist, Dr. Craig Venter [...] proposed that instead of sequencing the [...] entire human genome, only the genes that code [...]for actual proteins should be sequenced [...]which would be much easier since genes make up only 2% of the DNA. youlinmagazine.com |
通过CLIA认证的基因测试、全外显子组或 全 基因组 测 序 、各种有针对性的试验以及关键的生物信息、分析工具和解释性指导方针的结合，将能够为患上罕见的、原因不明的疾病或复杂疾病的患者提供及时、明确的诊断。 tipschina.gov.cn | The combination of [...] CLIA-validated genetic testing, whole exome or whole genome sequencing [...]and broad targeted assays, along [...]with critical bioinformatics, analytic tools, and interpretative guidelines will contribute to timely definitive diagnoses for patients with rare, unexplained diseases or complex diseases; in essence, this integration will speed delivery of genomic test results and improve patient care. tipschina.gov.cn |
作者会喜欢到感谢博士斯蒂芬金斯莫尔和的儿 科 基因组 医 学中心儿童慈悲医院和诊所为他们的计算集群为我们的数据分析的，Illumina公司的现场服务团队（伊丽莎白·博耶，斯科特·库克和马克库克）和技术顾问团队，为他们的快速反应和下一代DNA测序仪，HiScanSQ，和数据质量分析的运行有用的建议。 jove.com | The authors would like to thank Dr. Stephen Kingsmore [...] and the Pediatric Genome Medicine Center [...]at Children's Mercy Hospitals and Clinics [...]for the use of their computing clusters for our data analysis, Illumina's field service team (Elizabeth Boyer, Scott Cook and Mark Cook) and technical consultant team for their quick responses and helpful suggestions on the running of the next generation DNA sequencing instrument, HiScanSQ, and data quality analysis. jove.com |
这些应用得益于使用了至少两种优化计算处理器的系统，包涵 在 基因组 信 息学、互联网数据处理、商业处理优化以及大多数非64字节浮点高性能计算（HPC）的应用中。 tipschina.gov.cn | The applications that benefit from a system with at [...] least two optimized compute processor types [...] are those within genome informatics, Internet [...]data processing, business process [...]optimization, and most non 64-bit floating point HPC applications. tipschina.gov.cn |
英汉双解词典包含2273206条英汉词条，基本涵盖了全部常用单词的翻译及用法，是英语学习的有利工具。