1
- (of a person) without money, a job, or a place to live; destitute（人）穷困的; 赤贫的：
a novel about being down and out in London.
一部描写伦敦贫困情况的小说。
2
- (of a boxer) knocked down and unable to continue fighting（拳击手）被击倒而无法继续比赛的。
2.1
- (of a competitor) facing certain defeat（竞争者）面临失败的。
noun
down-and-out
- a person without money, a job, or a place to live穷困潦倒的人：
a hostel for down-and-outs.
供无家可归者住宿的收容所。