I was unhappy and really messed up.
我不开心, 情绪极差。
the wreck messed him up so much that he can't walk.
事故使他受伤不轻, 到现在还不能走动。
See main entry:mess
英汉双解词典包含131075条英汉词条,基本涵盖了全部常用单词的翻译及用法,是英语学习的有利工具。