incapacity

Who will run the company in the event of your death or incapacity? [=if you die or become unable to run it]如果你去世或无法工作，谁来管理这家公司呢？

I'm aware of my weaknesses and incapacities.我意识到自己的弱点和无能。

They have a complete incapacity for dealing with numbers. [=they are not able to deal with numbers]他们完全没有跟数字打交道的能力。