havoc

the havoc of war战争的浩劫

A powerful tornado wreaked havoc on [=caused great destruction to] the small village.一场猛烈的龙卷风给这个小村庄造成了极大的破坏。

The disease can play havoc with the body's immune system.这种疾病会严重破坏人体的免疫系统。

Several small children can create/cause havoc in a house.几个小孩子就可以让整个房子乱翻天。