fateful

She made the fateful [=momentous] decision to go back home to face her mother.她做出了回家面对母亲的重大决定。

His life changed on that fateful November evening.在那个决定其命运的十一月的夜晚，他的人生被改写。

Hundreds perished on that fateful day.数百人在那个灾难性的日子失去了生命。

Her campaign took a fateful turn.她的竞选形势急转直下。