:to be the end, failure, or death of (someone or something)完蛋；失败；灭亡
It looks like it's curtains for the mayor after this election. [=the mayor will not be elected again]经过此次选举，市长的仕途看来走到尽头了。
If they don't win today's game, it'll be/mean/spell curtains for their hopes of winning the championship. [=their hopes will be ended]如果他们不能赢得今天的比赛，夺冠的希望就将成为泡影。