If you keep working so hard, the stress will eventually take its toll. [=your health will be harmed]如果你继续这么辛苦地工作，最终会被压垮的。

The stress will take its toll on you.压力会把你压垮的。

Too much sunlight can take a (heavy) toll on your skin. [=can harm your skin]过多的阳光会对你的皮肤造成（严重）伤害。

Her illness has taken a toll on her marriage.她的疾病已严重影响了她的婚姻。