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单词 Cyclohexanediamine
释义

Cyclohexanediamine

英语百科

trans-1,2-Diaminocyclohexane

Oxaliplatin, a complex of R,R-diaminocyclohexane, is an important anticancer drug.

trans-1,2-Diaminocyclohexane is an organic compound with the formula C6H10(NH2)2. This diamine is a building block for chiral ligands that are useful in asymmetric catalysis.

A mixture of cis- and trans-1,2-diaminocyclohexane is produced by the hydrogenation of o-phenylenediamine. The racemic trans isomer [1:1 mixture of (1R,2R)-1,2-diaminocyclohexane and (1S,2S)-1,2-diaminocyclohexane] can be separated into the two enantiomers using enantiomerically pure tartaric acid as the resolving agent.

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